| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Gamma-aminobutyric acid receptor subunit alpha-3 |
|---|
| Ligand | BDBM85196 |
|---|
| Substrate/Competitor | n/a |
|---|
| Ki | 37.15±n/a nM |
|---|
| Comments | PDSP_1846 |
|---|
| Citation |  Ebert, B; Thompson, SA; Saounatsou, K; McKernan, R; Krogsgaard-Larsen, P; Wafford, KA Differences in agonist/antagonist binding affinity and receptor transduction using recombinant human gamma-aminobutyric acid type A receptors. Mol Pharmacol52:1150-6 (1997) [PubMed] |
|---|
| More Info.: | Get all data from this article |
|---|
| |
| Gamma-aminobutyric acid receptor subunit alpha-3 |
|---|
| Name: | Gamma-aminobutyric acid receptor subunit alpha-3 |
|---|
| Synonyms: | GABA A Alpha3Beta3Gamma2 | GABA A receptor alpha-3/beta-2/gamma-2 | GABA C | GABA receptor alpha-3 subunit | GABA-A receptor | GABRA3 | GBRA3_HUMAN | Gamma-aminobutyric acid receptor subunit alpha-3 | agonist GABA site |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 55175.47 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | GABA A Alpha3Beta1Gamma2 0 HUMAN::P34903 |
|---|
| Residue: | 492 |
|---|
| Sequence: | MIITQTSHCYMTSLGILFLINILPGTTGQGESRRQEPGDFVKQDIGGLSPKHAPDIPDDS
TDNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQ
TWHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLL
YTMRLTIHAECPMHLEDFPMDVHACPLKFGSYAYTTAEVVYSWTLGKNKSVEVAQDGSRL
NQYDLLGHVVGTEIIRSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLN
RESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVN
YFTKRSWAWEGKKVPEALEMKKKTPAAPAKKTSTTFNIVGTTYPINLAKDTEFSTISKGA
APSASSTPTIIASPKATYVQDSPTETKTYNSVSKVDKISRIIFPVLFAIFNLVYWATYVN
RESAIKGMIRKQ
|
|
|
|---|
| BDBM85196 |
|---|
| n/a |
|---|
| Name | BDBM85196 |
|---|
| Synonyms: | CAS_5448 | NSC_5448 | Thiomuscimol |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C4H6N2OS |
|---|
| Mol. Mass. | 130.168 |
|---|
| SMILES | NCc1cc(=O)[nH]s1 |
|---|
| Structure | 
|
|---|
Search and Browse
