Reaction Details |
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Target | Norepinephrine transporter |
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Ligand | BDBM22416 |
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Substrate/Competitor | n/a |
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Ki | 59±n/a nM |
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Comments | PDSP_1439 |
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Citation | Owens, MJ; Morgan, WN; Plott, SJ; Nemeroff, CB Neurotransmitter receptor and transporter binding profile of antidepressants and their metabolites. J Pharmacol Exp Ther283:1305-22 (1997) [PubMed] |
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More Info.: | Get all data from this article |
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Norepinephrine transporter |
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Name: | Norepinephrine transporter |
Synonyms: | n/a |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 2082.45 |
Organism: | RAT |
Description: | Norepinephrine transporter 0 RAT::Q9JIA2 |
Residue: | 19 |
Sequence: | |
BDBM22416 |
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n/a |
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Name | BDBM22416 |
Synonyms: | (3S,4R)-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine | (3S,4R)-3-[(2H-1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine | CHEMBL490 | PAROXETINE | US09969700, Paroxetine | US9944618, Compound ID No. 182 | [3H]Paroxetine |
Type | radiolabeled ligand |
Emp. Form. | C19H20FNO3 |
Mol. Mass. | 329.3654 |
SMILES | Fc1ccc(cc1)[C@@H]1CCNC[C@H]1COc1ccc2OCOc2c1 |
Structure |
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