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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Sodium-dependent noradrenaline transporter | ||
| Ligand | BDBM50005548 | ||
| Substrate/Competitor | n/a | ||
| Ki | 15.6±n/a nM | ||
| Comments | PDSP_1347 | ||
| Citation |  Tatsumi, M; Groshan, K; Blakely, RD; Richelson, E Pharmacological profile of antidepressants and related compounds at human monoamine transporters. Eur J Pharmacol340:249-58 (1997) [PubMed] Article | ||
| More Info.: | Get all data from this article | ||
| Sodium-dependent noradrenaline transporter | |||
| Name: | Sodium-dependent noradrenaline transporter | ||
| Synonyms: | Monoamine transporter | NAT1 | NET | NET1 | Noradrenaline Transporter (NET) | Norepinephrine Transporter (NET) | Norepinephrine transporter protein (NET) | SC6A2_HUMAN | SLC6A2 | SLC6A5 | Sodium-dependent noradrenaline transporter (NET) | Solute carrier family 6 member 2 | ||
| Type: | Multi-pass membrane protein | ||
| Mol. Mass.: | 69337.72 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P23975 | ||
| Residue: | 617 | ||
| Sequence: |
| ||
| BDBM50005548 | |||
| n/a | |||
| Name | BDBM50005548 | ||
| Synonyms: | (+)-2-Methyl-4-phenyl-1,2,3,4-tetrahydro-isoquinolin-8-ylamine | (+/-)-2-Methyl-4-phenyl-1,2,3,4-tetrahydro-isoquinolin-8-ylamine | (-)-2-Methyl-4-phenyl-1,2,3,4-tetrahydro-isoquinolin-8-ylamine | (Nomifensine) 2-Methyl-4-phenyl-1,2,3,4-tetrahydro-isoquinolin-8-ylamine | 2-Methyl-4-phenyl-1,2,3,4-tetrahydro-isoquinolin-8-ylamine | 2-Methyl-4-phenyl-1,2,3,4-tetrahydro-isoquinolin-8-ylamine (Nomifensine) | 2-Methyl-4-phenyl-1,2,3,4-tetrahydro-isoquinolin-8-ylamine(Nomifensine) | 2-methyl-4-phenyl-1,2,3,4-tetrahydroisoquinolin-8-amine | CHEMBL273575 | NOMIFENSINE | NOMIFENSINE2-Methyl-4-phenyl-1,2,3,4-tetrahydro-isoquinolin-8-ylamine | ||
| Type | Small organic molecule | ||
| Emp. Form. | C16H18N2 | ||
| Mol. Mass. | 238.3275 | ||
| SMILES | CN1CC(c2ccccc2)c2cccc(N)c2C1 | ||
| Structure | 
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