| Reaction Details |
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 | Report a problem with these data |
| Target | Alpha-2A adrenergic receptor |
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| Ligand | BDBM50241196 |
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| Substrate/Competitor | n/a |
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| Ki | 13.18±n/a nM |
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| Comments | PDSP_3304 |
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| Citation |  Jasper, JR; Lesnick, JD; Chang, LK; Yamanishi, SS; Chang, TK; Hsu, SA; Daunt, DA; Bonhaus, DW; Eglen, RM Ligand efficacy and potency at recombinant alpha2 adrenergic receptors: agonist-mediated [35S]GTPgammaS binding. Biochem Pharmacol55:1035-43 (1998) [PubMed] Article |
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| More Info.: | Get all data from this article |
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| Alpha-2A adrenergic receptor |
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| Name: | Alpha-2A adrenergic receptor |
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| Synonyms: | ADA2A_HUMAN | ADRA2A | ADRA2R | ADRAR | Adrenergic alpha2A | Adrenergic receptor alpha | Alpha-2 adrenergic receptor subtype C10 | Alpha-2A adrenoceptor | Alpha-2A adrenoreceptor | Alpha-2AAR | alpha-2A adrenergic receptor [Homo sapiens] |
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| Type: | Enzyme |
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| Mol. Mass.: | 48979.91 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P08913 |
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| Residue: | 465 |
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| Sequence: | MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLML
LTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAW
CEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVIS
FPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKR
RTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGP
RDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTP
AAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPR
TLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV
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| BDBM50241196 |
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| n/a |
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| Name | BDBM50241196 |
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| Synonyms: | (R)-5-(1-(2,3-dimethylphenyl)ethyl)-1H-imidazole | 4-[(R)-1-(2,3-Dimethyl-phenyl)-ethyl]-1H-imidazole | CHEMBL397901 | Dexmedetomidine |
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| Type | Small organic molecule |
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| Emp. Form. | C13H16N2 |
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| Mol. Mass. | 200.2795 |
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| SMILES | C[C@@H](c1cnc[nH]1)c1cccc(C)c1C |
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| Structure | 
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