| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Alpha-2A adrenergic receptor |
|---|
| Ligand | BDBM30712 |
|---|
| Substrate/Competitor | n/a |
|---|
| Ki | 15.49±n/a nM |
|---|
| Comments | PDSP_1428 |
|---|
| Citation |  Jasper, JR; Lesnick, JD; Chang, LK; Yamanishi, SS; Chang, TK; Hsu, SA; Daunt, DA; Bonhaus, DW; Eglen, RM Ligand efficacy and potency at recombinant alpha2 adrenergic receptors: agonist-mediated [35S]GTPgammaS binding. Biochem Pharmacol55:1035-43 (1998) [PubMed] Article |
|---|
| More Info.: | Get all data from this article |
|---|
| |
| Alpha-2A adrenergic receptor |
|---|
| Name: | Alpha-2A adrenergic receptor |
|---|
| Synonyms: | ADRA2A | Alpha-2A adrenergic receptor | adrenergic Alpha2A |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 48888.08 |
|---|
| Organism: | MOUSE |
|---|
| Description: | adrenergic Alpha2A ADRA2A MOUSE::Q01338 |
|---|
| Residue: | 450 |
|---|
| Sequence: | MGSLQPDAGNSSWNGTEAPGGGTRATPYSLQVTLTLVCLAGLLMLFTVFGNVLVIIAVFT
SRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKVWCEIYLALDVLFCTSS
IVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIVTVWVISAVISFPPLISIEKKGAGGG
QQPAEPSCKINDQKWYVISSSIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDACS
APPGGADRRPNGLGPERGAGPTGAEAEPLPTQLNGAPGEPAPAGPRDGDALDLEESSSSE
HAERPPGPRRPDRGPRAKGKTRASQVKPGDSLPRRGPGAAGPGASGSGHGEERGGGAKAS
RWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLIAVGCPVPSQLFNFFFWFGYCNSS
LNPVIYTIFNHDFRRAFKKILCRGDRKRIV
|
|
|
|---|
| BDBM30712 |
|---|
| n/a |
|---|
| Name | BDBM30712 |
|---|
| Synonyms: | 6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimethyl-phenol;hydrochloride | 6-tert-butyl-3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-2,4-dimethyl-phenol;hydrochloride | 6-tert-butyl-3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-2,4-dimethylphenol;hydrochloride | MLS000038040 | Oxymetazoline | SMR000059324 | cid_66259 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C16H24N2O |
|---|
| Mol. Mass. | 260.3746 |
|---|
| SMILES | Cc1cc(c(O)c(C)c1CC1=NCCN1)C(C)(C)C |t:11| |
|---|
| Structure | 
|
|---|
Search and Browse
