| Reaction Details |
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 | Report a problem with these data |
| Target | Glutamine--fructose-6-phosphate aminotransferase [isomerizing] |
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| Ligand | BDBM85312 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Enzyme Assay |
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| pH | 6.85±0 |
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| Ki | 900000±0.0 nM |
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| IC50 | 2000000±0.0 nM |
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| Citation |  Milewski, S; Hoffmann, M; Andruszkiewicz, R; Borowski, E Investigation of Mechanism of Nitrogen Transfer in Glucosamine 6-Phosphate Synthase with the Use of Transition State Analogs Bioorg Chem25:283-296 (1997) |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Glutamine--fructose-6-phosphate aminotransferase [isomerizing] |
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| Name: | Glutamine--fructose-6-phosphate aminotransferase [isomerizing] |
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| Synonyms: | GFA1 | GFA1_CANAL | Glucosamine-6- Phosphate Synthase |
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| Type: | Enzyme |
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| Mol. Mass.: | 79262.13 |
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| Organism: | Candida albicans |
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| Description: | P53704 |
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| Residue: | 713 |
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| Sequence: | MCGIFGYVNFLVDKSKGEIIDNLIEGLQRLEYRGYDSAGIAVDGKLTKDPSNGDEEYMDS
IIIKTTGKVKVLKQKIIDDQIDRSAIFDNHVGIAHTRWATHGQPKTENCHPHKSDPKGEF
IVVHNGIITNYAALRKYLLSKGHVFESETDTECIAKLFKHFYDLNVKAGVFPDLNELTKQ
VLHELEGSYGLLVKSYHYPGEVCGTRKGSPLLVGVKTDKKLKVDFVDVEFEAQQQHRPQQ
PQINHNGATSAAELGFIPVAPGEQNLRTSQSRAFLSEDDLPMPVEFFLSSDPASVVQHTK
KVLFLEDDDIAHIYDGELRIHRASTKSAGESTVRPIQTLEMELNEIMKGPYKHFMQKEIF
EQPDSAFNTMRGRIDFENCVVTLGGLKSWLSTIRRCRRIIMIACGTSYHSCLATRSIFEE
LTEIPVSVELASDFLDRRSPVFRDDTCVFVSQSGETADSILALQYCLERGALTVGIVNSV
GSSMSRQTHCGVHINAGPEIGVASTKAYTSQYIALVMFALSLSNDSISRKGRHEEIIKGL
QKIPEQIKQVLKLENKIKDLCNSSLNDQKSLLLLGRGYQFATALEGALKIKEISYMHSEG
VLAGELKHGILALVDEDLPIIAFATRDSLFPKVMSAIEQVTARDGRPIVICNEGDAIISN
DKVHTTLEVPETVDCLQGLLNVIPLQLISYWLAVNRGIDVDFPRNLAKSVTVE
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| BDBM85312 |
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| n/a |
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| Name | BDBM85312 |
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| Synonyms: | GlcN-6-P synthase inhibitor, 5 (racemic mixture) |
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| Type | Small organic molecule |
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| Emp. Form. | C5H12NO5P |
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| Mol. Mass. | 197.1262 |
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| SMILES | COP(O)(=O)CCC(N)C(O)=O |
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| Structure | 
|
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