| Reaction Details |
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 | Report a problem with these data |
| Target | Prostaglandin E2 receptor EP3 subtype |
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| Ligand | BDBM85178 |
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| Substrate/Competitor | n/a |
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| Ki | 25±n/a nM |
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| Comments | PDSP_1237 |
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| Citation |  Sharif, NA; Xu, SX; Williams, GW; Crider, JY; Griffin, BW; Davis, TL Pharmacology of [3H]prostaglandin E1/[3H]prostaglandin E2 and [3H]prostaglandin F2alpha binding to EP3 and FP prostaglandin receptor binding sites in bovine corpus luteum: characterization and correlation with functional data. J Pharmacol Exp Ther286:1094-102 (1998) [PubMed] |
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| More Info.: | Get all data from this article |
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| Prostaglandin E2 receptor EP3 subtype |
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| Name: | Prostaglandin E2 receptor EP3 subtype |
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| Synonyms: | PE2R3_BOVIN | PTGER3 | Prostaglandin E3 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 46379.75 |
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| Organism: | BOVINE |
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| Description: | Prostaglandin E3 PTGER3 BOVINE::P34979 |
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| Residue: | 417 |
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| Sequence: | MKATRDHASAPFCTRFNHSDPGIWAAERAVEAPNNLTLPPEPSEDCGSVSVAFSMTMMIT
GFVGNALAITLVSKSYRRREGKRKKSFLLCIGWLALTDMVGQLLTSPVVIVLYLSHQRWE
QLDPSGRLCTFFGLTMTVFGLSSLFIASAMAVERALATRAPHWYSSHMKTSVTRAVLLGV
WLAVLAFALLPVLGVGQYTIQWPGTWCFISTGPGGNGTNSRQNWGNVFFASAFAILGLSA
LVVTFACNLATIKALVSRCRAKATASQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLIM
MLKMIFNHTSVEHCKTYTENQDECNFFLIAVRLASLNQILDPWVYLLLRKILLQKFCQLL
KGHSYGLDTEGGTENKDKEMKENLYISNLSRFFILLGHFTEARRGRGHIYLHTLEHQ
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| BDBM85178 |
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| n/a |
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| Name | BDBM85178 |
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| Synonyms: | CAS_59122-46-2 | MISOPROSTOL | MISOPROSTOL (Methyl Ester) | NSC_5282381 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H38O5 |
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| Mol. Mass. | 382.5341 |
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| SMILES | CCCCC(C)(O)CC=CC1C(O)CC(=O)C1CCCCCCC(=O)OC |w:8.7| |
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| Structure | 
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