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TargetProstaglandin F2-alpha receptor
LigandBDBM50109546
Substrate/Competitorn/a
Ki>10000±n/a nM
CommentsPDSP_1472
Citation Sharif, NAXu, SXWilliams, GWCrider, JYGriffin, BWDavis, TL Pharmacology of [3H]prostaglandin E1/[3H]prostaglandin E2 and [3H]prostaglandin F2alpha binding to EP3 and FP prostaglandin receptor binding sites in bovine corpus luteum: characterization and correlation with functional data. J Pharmacol Exp Ther286:1094-102 (1998) [PubMed]
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Prostaglandin F2-alpha receptor
Name:Prostaglandin F2-alpha receptor
Synonyms:PF2R_BOVIN | PGF receptor | PGF2 alpha receptor | PTGFR | ProstaglandinF2Alpha | Prostanoid FP receptor
Type:Enzyme Catalytic Domain
Mol. Mass.:41044.75
Organism:BOVINE
Description:ProstaglandinF2Alpha PTGFR BOVINE::P37289
Residue:362
Sequence:
MSTNSSIQPVSPESELLSNTTCQLEEDLSISFSIIFMTVGILSNSLAIAILMKAYQRFRQ
KYKSSFLLLASALVITDFFGHLINGTIAVFVYASDKDWIYFDKSNILCSIFGICMVFSGL
CPLFLGSLMAIERCIGVTKPIFHSTKITTKHVKMMLSGVCFFAVFVALLPILGHRDYKIQ
ASRTWCFYKTDEIKDWEDRFYLLLFAFLGLLALGISFVCNAITGISLLKVKFRSQQHRQG
RSHHFEMVIQLLGIMCVSCICWSPFLVTMASIGMNIQDFKDSCERTLFTLRMATWNQILD
PWVYILLRKAVLRNLYVCTRRCCGVHVISLHVWELSSIKDSLKVAAISDLPVTEKVTQQT
ST
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BDBM50109546
n/a
NameBDBM50109546
Synonyms:5-[(3aS,4R,5R,6aS)-5-Hydroxy-4-((S)-3-hydroxy-oct-1-enyl)-hexahydro-pentalen-(2Z)-ylidene]-pentanoic acid | 5-[5-Hydroxy-4-(3-hydroxy-oct-1-enyl)-hexahydro-pentalen-2-ylidene]-pentanoic acidCarbacyclin | CARBACYCLIN | CHEMBL148319 | PGI2
TypeSmall organic molecule
Emp. Form.C21H34O4
Mol. Mass.350.4923
SMILESCCCCC[C@H](O)\C=C\[C@H]1[C@H](O)C[C@@H]2C\C(C[C@H]12)=C\CCCC(O)=O
Structure
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