| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Delta-type opioid receptor |
|---|
| Ligand | BDBM50041958 |
|---|
| Substrate/Competitor | n/a |
|---|
| Ki | 9153±n/a nM |
|---|
| Comments | PDSP_2917 |
|---|
| Citation |  Spetea, M; Otvös, F; Tóth, G; Nguyen, TM; Schiller, PW; Vogel, Z; Borsodi, A Interaction of agonist peptide [3H]Tyr-D-Ala-Phe-Phe-NH2 with mu-opioid receptor in rat brain and CHO-mu/1 cell line. Peptides19:1091-8 (1998) [PubMed] Article |
|---|
| More Info.: | Get all data from this article |
|---|
| |
| Delta-type opioid receptor |
|---|
| Name: | Delta-type opioid receptor |
|---|
| Synonyms: | Cytochrome P450 3A4 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor | Delta-type opioid receptor (DOR) | OPIATE Delta | OPRD_RAT | Opiate Delta 1 | Opioid receptor | Opioid receptor A | Opioid receptors; mu & delta | Oprd1 | Ror-a | Voltage-gated potassium channel |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 40465.04 |
|---|
| Organism: | Rattus norvegicus (rat) |
|---|
| Description: | Competition binding assays were using CHO-K1 cell membranes expressing the opioid receptor. |
|---|
| Residue: | 372 |
|---|
| Sequence: | MEPVPSARAELQFSLLANVSDTFPSAFPSASANASGSPGARSASSLALAIAITALYSAVC
AVGLLGNVLVMFGIVRYTKLKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELL
CKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVG
VPIMVMAVTQPRDGAVVCTLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRL
RSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDINRRDPLVVAAL
HLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRAPCGGQEPGSLRRPRQATARERVTAC
TPSDGPGGGAAA
|
|
|
|---|
| BDBM50041958 |
|---|
| n/a |
|---|
| Name | BDBM50041958 |
|---|
| Synonyms: | 2-(1-{2-[2-amino-3-(4-hydroxyphenyl)propanoyl]-1,2,3,4-tetrahydro-3-isoquinolinylmethylamino}-2-phenylethylcarboxamido)-3-phenylpropanoic acid | 2-[1-{2-[2-amino-3-(4-hydroxyphenyl)-(2S)-propanoyl]-1,2,3,4-tetrahydro-3-isoquinolinylcarboxamido}-2-phenyl-(1S)-ethylcarboxamido]-3-phenyl-(2S)-propanoic acid | CHEMBL108731 | TIPP |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C37H38N4O6 |
|---|
| Mol. Mass. | 634.7208 |
|---|
| SMILES | N[C@@H](Cc1ccc(O)cc1)C(=O)N1Cc2ccccc2CC1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(O)=O |
|---|
| Structure | 
|
|---|
Search and Browse
