| Reaction Details |
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 | Report a problem with these data |
| Target | Capsid scaffolding protein |
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| Ligand | BDBM275767 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | HCMV antiviral assay |
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| EC50 | 450±0.09 nM |
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| Citation |  Hostetler, KY; Beadle, JR Phosphonate compounds US Patent US10071110 Publication Date 9/11/2018 |
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| More Info.: | Get all data from this article, Assay Method |
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| Capsid scaffolding protein |
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| Name: | Capsid scaffolding protein |
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| Synonyms: | APNG | Assemblin | Assembly protein | Capsid protein P40 | Human cytomegalovirus protease (HCMV Pr) | Human herpes virus 5 capsid protein P40 | Protease precursor | SCAF_HCMVA | UL80 | pPR |
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| Type: | PROTEIN |
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| Mol. Mass.: | 73854.16 |
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| Organism: | Human cytomegalovirus (strain AD169) (HHV-5) (Human herpesvirus 5) |
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| Description: | ChEMBL_158958 |
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| Residue: | 708 |
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| Sequence: | MTMDEQQSQAVAPVYVGGFLARYDQSPDEAELLLPRDVVEHWLHAQGQGQPSLSVALPLN
INHDDTAVVGHVAAMQSVRDGLFCLGCVTSPRFLEIVRRASEKSELVSRGPVSPLQPDKV
VEFLSGSYAGLSLSSRRCDDVEAATSLSGSETTPFKHVALCSVGRRRGTLAVYGRDPEWV
TQRFPDLTAADRDGLRAQWQRCGSTAVDASGDPFRSDSYGLLGNSVDALYIRERLPKLRY
DKQLVGVTERESYVKASVSPEAACDIKAASAERSGDSRSQAATPAAGARVPSSSPSPPVE
PPSPVQPPALPASPSVLPAESPPSLSPSEPAEAASMSHPLSAAVPAATAPPGATVAGASP
AVSSLAWPHDGVYLPKDAFFSLLGASRSAVPVMYPGAVAAPPSASPAPLPLPSYPASYGA
PVVGYDQLAARHFADYVDPHYPGWGRRYEPAPSLHPSYPVPPPPSPAYYRRRDSPGGMDE
PPSGWERYDGGHRGQSQKQHRHGGSGGHNKRRKETAAASSSSSDEDLSFPGEAEHGRARK
RLKSHVNSDGGSGGHAGSNQQQQQRYDELRDAIHELKRDLFAARQSSTLLSAALPSAASS
SPTTTTVCTPTGELTSGGGETPTALLSGGAKVAERAQAGVVNASCRLATASGSEAATAGP
STAGSSSCPASVVLAAAAAQAAAASQSPPKDMVDLNRRIFVAALNKLE
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| BDBM275767 |
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| n/a |
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| Name | BDBM275767 |
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| Synonyms: | US10071110, Compound CDV | US10071110, Compound Cidofovir(CDV) |
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| Type | Small organic molecule |
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| Emp. Form. | C8H14N3O6P |
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| Mol. Mass. | 279.187 |
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| SMILES | Nc1ccn(CC(CO)OCP(O)(O)=O)c(=O)n1 |
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| Structure | 
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