| Reaction Details |
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 | Report a problem with these data |
| Target | Melatonin receptor type 1B |
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| Ligand | BDBM85065 |
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| Substrate/Competitor | n/a |
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| Ki | 26.91±n/a nM |
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| Comments | PDSP_1123 |
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| Citation |  Teh, MT; Sugden, D Comparison of the structure-activity relationships of melatonin receptor agonists and antagonists: lengthening the N-acyl side-chain has differing effects on potency on Xenopus melanophores. Naunyn Schmiedebergs Arch Pharmacol358:522-8 (1998) [PubMed] Article |
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| More Info.: | Get all data from this article |
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| Melatonin receptor type 1B |
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| Name: | Melatonin receptor type 1B |
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| Synonyms: | MTNR1B | MTR1B_HUMAN | Mel-1B-R | Mel1b melatonin receptor | Melatonin 1B | Melatonin receptor | Melatonin receptor type 1B | Melatonin receptor type 2 (MT2) |
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| Type: | Enzyme |
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| Mol. Mass.: | 40203.54 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P49286 |
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| Residue: | 362 |
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| Sequence: | MSENGSFANCCEAGGWAVRPGWSGAGSARPSRTPRPPWVAPALSAVLIVTTAVDVVGNLL
VILSVLRNRKLRNAGNLFLVSLALADLVVAFYPYPLILVAIFYDGWALGEEHCKASAFVM
GLSVIGSVFNITAIAINRYCYICHSMAYHRIYRRWHTPLHICLIWLLTVVALLPNFFVGS
LEYDPRIYSCTFIQTASTQYTAAVVVIHFLLPIAVVSFCYLRIWVLVLQARRKAKPESRL
CLKPSDLRSFLTMFVVFVIFAICWAPLNCIGLAVAINPQEMAPQIPEGLFVTSYLLAYFN
SCLNAIVYGLLNQNFRREYKRILLALWNPRHCIQDASKGSHAEGLQSPAPPIIGVQHQAD
AL
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| BDBM85065 |
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| n/a |
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| Name | BDBM85065 |
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| Synonyms: | CAS_117946-91-5 | Luzindole | NSC_122162 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H20N2O |
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| Mol. Mass. | 292.3749 |
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| SMILES | CC(=O)NCCc1c(Cc2ccccc2)[nH]c2ccccc12 |
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| Structure | 
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