Reaction Details | |||
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Target | Corticotropin-releasing factor receptor 2 | ||
Ligand | BDBM50058163 | ||
Substrate/Competitor | n/a | ||
Ki | >10000±n/a nM | ||
Comments | PDSP_570 | ||
Citation | Okuyama, S; Chaki, S; Kawashima, N; Suzuki, Y; Ogawa, S; Nakazato, A; Kumagai, T; Okubo, T; Tomisawa, K Receptor binding, behavioral, and electrophysiological profiles of nonpeptide corticotropin-releasing factor subtype 1 receptor antagonists CRA1000 and CRA1001. J Pharmacol Exp Ther289:926-35 (1999) [PubMed] | ||
More Info.: | Get all data from this article | ||
Corticotropin-releasing factor receptor 2 | |||
Name: | Corticotropin-releasing factor receptor 2 | ||
Synonyms: | CRF-R-2 | CRF-R2 | CRF2 Beta | CRFR-2 | CRFR2_RAT | CRH-R-2 | CRH-R2 | Corticotropin releasing factor receptor | Corticotropin-releasing factor receptor 2 | Corticotropin-releasing hormone receptor 2 | Crf2r | Crhr2 | ||
Type: | Enzyme Catalytic Domain | ||
Mol. Mass.: | 47697.09 | ||
Organism: | RAT | ||
Description: | CRF2 Beta 0 RAT::P47866 | ||
Residue: | 411 | ||
Sequence: |
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BDBM50058163 | |||
n/a | |||
Name | BDBM50058163 | ||
Synonyms: | Butyl-[2,5-dimethyl-7-(2,4,6-trimethyl-phenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]-ethyl-amine | CHEMBL9946 | CP 154,526 | CP-154526 | N-butyl-N-ethyl-7-mesityl-2,5-dimethyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine | ||
Type | Small organic molecule | ||
Emp. Form. | C23H32N4 | ||
Mol. Mass. | 364.527 | ||
SMILES | CCCCN(CC)c1nc(C)nc2n(cc(C)c12)-c1c(C)cc(C)cc1C |(-10.62,2.69,;-9.29,3.46,;-7.95,2.7,;-6.62,3.48,;-5.28,2.71,;-3.95,3.49,;-3.96,5.03,;-5.27,1.17,;-6.6,.4,;-6.6,-1.14,;-7.94,-1.91,;-5.27,-1.91,;-3.92,-1.14,;-2.44,-1.61,;-1.54,-.35,;-2.46,.9,;-1.99,2.37,;-3.93,.41,;-1.96,-3.07,;-2.99,-4.22,;-4.49,-3.91,;-2.5,-5.68,;-.99,-5.99,;-.51,-7.46,;.03,-4.83,;-.46,-3.38,;.56,-2.22,)| | ||
Structure |