| Reaction Details |
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 | Report a problem with these data |
| Target | Hexokinase-1 |
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| Ligand | BDBM85424 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Enzyme Inhibition Assay |
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| pH | 7.6±0 |
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| Temperature | 298.15±0 K |
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| IC50 | 6000000±0.0 nM |
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| Citation |  Willson, M; Alric, I; Perie, J; Sanejouand, YH Yeast hexokinase inhibitors designed from the 3-D enzyme structure rebuilding. J Enzym Inhib12:101-21 (1997) [PubMed] Article |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Hexokinase-1 |
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| Name: | Hexokinase-1 |
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| Synonyms: | HKA | HXK1 | HXKA_YEAST | Hexokinase |
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| Type: | Protein |
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| Mol. Mass.: | 53728.20 |
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| Organism: | Saccharomyces cerevisiae |
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| Description: | P04806 |
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| Residue: | 485 |
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| Sequence: | MVHLGPKKPQARKGSMADVPKELMDEIHQLEDMFTVDSETLRKVVKHFIDELNKGLTKKG
GNIPMIPGWVMEFPTGKESGNYLAIDLGGTNLRVVLVKLSGNHTFDTTQSKYKLPHDMRT
TKHQEELWSFIADSLKDFMVEQELLNTKDTLPLGFTFSYPASQNKINEGILQRWTKGFDI
PNVEGHDVVPLLQNEISKRELPIEIVALINDTVGTLIASYYTDPETKMGVIFGTGVNGAF
YDVVSDIEKLEGKLADDIPSNSPMAINCEYGSFDNEHLVLPRTKYDVAVDEQSPRPGQQA
FEKMTSGYYLGELLRLVLLELNEKGLMLKDQDLSKLKQPYIMDTSYPARIEDDPFENLED
TDDIFQKDFGVKTTLPERKLIRRLCELIGTRAARLAVCGIAAICQKRGYKTGHIAADGSV
YNKYPGFKEAAAKGLRDIYGWTGDASKDPITIVPAEDGSGAGAAVIAALSEKRIAEGKSL
GIIGA
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| BDBM85424 |
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| n/a |
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| Name | BDBM85424 |
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| Synonyms: | Glucosamine analog, 8 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H16N2O8 |
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| Mol. Mass. | 328.2747 |
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| SMILES | OCC1OC(O)C(NC(=O)c2cccc(c2)N(=O)=O)C(O)C1O |
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| Structure | 
|
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