| Reaction Details |
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 | Report a problem with these data |
| Target | Alpha-1A adrenergic receptor |
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| Ligand | BDBM50048392 |
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| Substrate/Competitor | n/a |
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| Ki | >10000±n/a nM |
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| Comments | PDSP_444 |
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| Citation |  Sánchez, C; Hyttel, J Comparison of the effects of antidepressants and their metabolites on reuptake of biogenic amines and on receptor binding. Cell Mol Neurobiol19:467-89 (1999) [PubMed] Article |
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| More Info.: | Get all data from this article |
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| Alpha-1A adrenergic receptor |
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| Name: | Alpha-1A adrenergic receptor |
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| Synonyms: | ADA1A_RAT | Adra1a | Adra1c | Alpha-1 adrenoreceptor | Alpha-1A adrenoceptor | Alpha-1A adrenoreceptor | Alpha-1C adrenergic receptor | adrenergic Alpha1A |
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| Type: | Protein |
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| Mol. Mass.: | 51620.15 |
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| Organism: | Rattus norvegicus (Rat) |
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| Description: | P43140 |
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| Residue: | 466 |
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| Sequence: | MVLLSENASEGSNCTHPPAPVNISKAILLGVILGGLIIFGVLGNILVILSVACHRHLHSV
THYYIVNLAVADLLLTSTVLPFSAIFEILGYWAFGRVFCNIWAAVDVLCCTASIMGLCII
SIDRYIGVSYPLRYPTIVTQRRGVRALLCVWVLSLVISIGPLFGWRQPAPEDETICQINE
EPGYVLFSALGSFYVPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKN
VPAEGGGVSSAKNKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPD
FKPSETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQCLRRRQSSKHALGYTL
HPPSQALEGQHRDMVRIPVGSGETFYKISKTDGVCEWKFFSSMPQGSARITVPKDQSACT
TARVRSKSFLQVCCCVGSSAPRPEENHQVPTIKIHTISLGENGEEV
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| BDBM50048392 |
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| n/a |
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| Name | BDBM50048392 |
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| Synonyms: | 2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one | BUPROPION | BUPROPION HYDROCHLORIDE | CHEMBL894 | US9944618, Compound ID No. 176 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H18ClNO |
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| Mol. Mass. | 239.741 |
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| SMILES | CC(NC(C)(C)C)C(=O)c1cccc(Cl)c1 |
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| Structure | 
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