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TargetAlpha-1A adrenergic receptor
LigandBDBM25870
Substrate/Competitorn/a
Ki 1600±n/a nM
CommentsPDSP_532
Citation Sánchez, CHyttel, J Comparison of the effects of antidepressants and their metabolites on reuptake of biogenic amines and on receptor binding. Cell Mol Neurobiol19:467-89 (1999) [PubMed]  Article
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Alpha-1A adrenergic receptor
Name:Alpha-1A adrenergic receptor
Synonyms:ADA1A_RAT | Adra1a | Adra1c | Alpha-1 adrenoreceptor | Alpha-1A adrenoceptor | Alpha-1A adrenoreceptor | Alpha-1C adrenergic receptor | adrenergic Alpha1A
Type:Protein
Mol. Mass.:51620.15
Organism:Rattus norvegicus (Rat)
Description:P43140
Residue:466
Sequence:
MVLLSENASEGSNCTHPPAPVNISKAILLGVILGGLIIFGVLGNILVILSVACHRHLHSV
THYYIVNLAVADLLLTSTVLPFSAIFEILGYWAFGRVFCNIWAAVDVLCCTASIMGLCII
SIDRYIGVSYPLRYPTIVTQRRGVRALLCVWVLSLVISIGPLFGWRQPAPEDETICQINE
EPGYVLFSALGSFYVPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKN
VPAEGGGVSSAKNKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPD
FKPSETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQCLRRRQSSKHALGYTL
HPPSQALEGQHRDMVRIPVGSGETFYKISKTDGVCEWKFFSSMPQGSARITVPKDQSACT
TARVRSKSFLQVCCCVGSSAPRPEENHQVPTIKIHTISLGENGEEV
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  Blast E-value cutoff:
BDBM25870
n/a
NameBDBM25870
Synonyms:1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile | CHEMBL549 | CITALOPRAM | CITALOPRAM HYDROBROMIDE | Escitalopram | [3H]Citalopram | [3H]Cytalopram | [3H]Escitalopram | [3H]Lexapro
Typeradiolabeled ligand
Emp. Form.C20H21FN2O
Mol. Mass.324.3919
SMILESCN(C)CCCC1(OCc2cc(ccc12)C#N)c1ccc(F)cc1
Structure
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