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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Histamine H1 receptor | ||
| Ligand | BDBM50020712 | ||
| Substrate/Competitor | n/a | ||
| Ki | 8.3±n/a nM | ||
| Comments | PDSP_288 | ||
| Citation |  Sánchez, C; Hyttel, J Comparison of the effects of antidepressants and their metabolites on reuptake of biogenic amines and on receptor binding. Cell Mol Neurobiol19:467-89 (1999) [PubMed] Article | ||
| More Info.: | Get all data from this article | ||
| Histamine H1 receptor | |||
| Name: | Histamine H1 receptor | ||
| Synonyms: | HISTAMINE H1 | HRH1_RAT | Hrh1 | ||
| Type: | Enzyme Catalytic Domain | ||
| Mol. Mass.: | 55716.35 | ||
| Organism: | RAT | ||
| Description: | HISTAMINE H1 HRH1 RAT::P31390 | ||
| Residue: | 486 | ||
| Sequence: |
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| BDBM50020712 | |||
| n/a | |||
| Name | BDBM50020712 | ||
| Synonyms: | 10,11-dihydro-5-(gamma-dimethylaminopropylidene)-5H-dibenzo(a,d)cycloheptene | 10,11-dihydro-N,N-dimethyl-5H-dibenzo(a,d)heptalene-Delta(5),gamma-propylamine | 3-(10,11-dihydro-5H-dibenzo(a,d)cyclohepten-5-ylidene)-N,N-dimethyl-1-propanamine | 3-(10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-ylidene)-N,N-dimethylpropan-1-amine | 3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethylpropan-1-amine | 5-(3-dimethylaminopropylidene)-10,11-dihydro-5H-dibenzo(a,d)cycloheptatriene | 5-(3-dimethylaminopropylidene)-10,11-dihydro-5H-dibenzo(a,d)cycloheptene | 5-(gamma-dimethylaminopropylidene)-5H-dibenzo[a,d][1,4]cycloheptadiene | AMITRIPTYLINE | Amitriptylin | CHEMBL629 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C20H23N | ||
| Mol. Mass. | 277.4033 | ||
| SMILES | [#6]-[#7](-[#6])-[#6]-[#6]\[#6]=[#6]-1/c2ccccc2-[#6]-[#6]-c2ccccc-12 | ||
| Structure | 
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