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Target5-hydroxytryptamine receptor 2B
LigandBDBM50024210
Substrate/Competitorn/a
Ki 29.51±n/a nM
CommentsPDSP_1920
Citation Porter, RH; Benwell, KR; Lamb, H; Malcolm, CS; Allen, NH; Revell, DF; Adams, DR; Sheardown, MJ Functional characterization of agonists at recombinant human 5-HT2A, 5-HT2B and 5-HT2C receptors in CHO-K1 cells. Br J Pharmacol128:13-20 (1999) [PubMed]  Article
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5-hydroxytryptamine receptor 2B
Name:5-hydroxytryptamine receptor 2B
Synonyms:5-HT-2B | 5-HT2B | 5-hydroxytryptamine (serotonin) receptor 2B [Homo sapiens] | 5-hydroxytryptamine receptor 2B (5-HT2B) | 5-hydroxytryptamine receptor 2C (5HT2C) | 5HT2B_HUMAN | HTR2B | Serotonin (5-HT3) receptor | Serotonin 2b (5-HT2b) receptor | Serotonin Receptor 2B
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:54312.47
Organism:Homo sapiens (Human)
Description:Receptor binding assays were performed using human clone stably expressed in CHO cells.
Residue:481
Sequence:
MALSYRVSELQSTIPEHILQSTFVHVISSNWSGLQTESIPEEMKQIVEEQGNKLHWAALL
ILMVIIPTIGGNTLVILAVSLEKKLQYATNYFLMSLAVADLLVGLFVMPIALLTIMFEAM
WPLPLVLCPAWLFLDVLFSTASIMHLCAISVDRYIAIKKPIQANQYNSRATAFIKITVVW
LISIGIAIPVPIKGIETDVDNPNNITCVLTKERFGDFMLFGSLAAFFTPLAIMIVTYFLT
IHALQKKAYLVKNKPPQRLTWLTVSTVFQRDETPCSSPEKVAMLDGSRKDKALPNSGDET
LMRRTSTIGKKSVQTISNEQRASKVLGIVFFLFLLMWCPFFITNITLVLCDSCNQTTLQM
LLEIFVWIGYVSSGVNPLVYTLFNKTFRDAFGRYITCNYRATKSVKTLRKRSSKIYFRNP
MAENSKFFKKHGIRNGINPAMYQSPMRLRSSTIQSSSIILLDTLLLTENEGDKTEEQVSY
V
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BDBM50024210
n/a
NameBDBM50024210
Synonyms:1H-indole-3-ethanamine | 2-(1H-indol-3-yl)ethanamine | 2-(3-indolyl)ethylamine | CHEMBL6640 | tryptamine
TypeSmall organic molecule
Emp. Form.C10H12N2
Mol. Mass.160.2157
SMILESNCCc1c[nH]c2ccccc12
Structure
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