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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Mu-type opioid receptor | ||
| Ligand | BDBM50028147 | ||
| Substrate/Competitor | n/a | ||
| Ki | 0.57±n/a nM | ||
| Comments | PDSP_441 | ||
| Citation |  Traynor, JR; Guo, L; Coop, A; Lewis, JW; Woods, JH Ring-constrained orvinols as analogs of buprenorphine: differences in opioid activity related to configuration of C(20) hydroxyl group. J Pharmacol Exp Ther291:1093-9 (1999) [PubMed] | ||
| More Info.: | Get all data from this article | ||
| Mu-type opioid receptor | |||
| Name: | Mu-type opioid receptor | ||
| Synonyms: | M-OR-1 | MOR-1 | Mu opioid receptor | Mu-type opioid receptor (Mu) | OPIATE Mu | OPRM1 | OPRM_CAVPO | ||
| Type: | Enzyme Catalytic Domain | ||
| Mol. Mass.: | 11165.58 | ||
| Organism: | GUINEA PIG | ||
| Description: | P97266 | ||
| Residue: | 98 | ||
| Sequence: |
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| BDBM50028147 | |||
| n/a | |||
| Name | BDBM50028147 | ||
| Synonyms: | 2-[3-cyclopropylmethyl-11-hydroxy-15-methoxy-(14R)-13-oxa-3-azahexacyclo[13.2.2.12,8.01,6.06,14.07,12]icosa-7,9,11-trien-16-yl]-3,3-dimethyl-2-butanol | 2-[3-cyclopropylmethyl-11-hydroxy-15-methoxy-(15S)-13-oxa-3-azahexacyclo[13.2.2.12,8.01,6.06,14.07,12]icosa-7,9,11-trien-16-yl]-3,3-dimethyl-2-butanol(Buprenorphine) | BUPRENORPHINE | Buprenorphine(+) | Buprenorphine(-) | Buprenorphine2-(3-cyclopropylmethyl-11-hydroxy-15-methoxy-13-oxa-3-azahexacyclo[13.2.2.12,8.01,6.06,14.07,12]icosa-7,9,11-trien-16-yl)-3,3-dimethyl-2-butanol( | CHEMBL560511 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C29H41NO4 | ||
| Mol. Mass. | 467.6401 | ||
| SMILES | CO[C@@]12CC[C@@]3(C[C@@H]1[C@@](C)(O)C(C)(C)C)[C@H]1Cc4ccc(O)c5O[C@@H]2[C@]3(CCN1CC1CC1)c45 |THB:8:7:25.24:4.3| | ||
| Structure | 
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