Reaction Details |
| Report a problem with these data |
Target | Somatostatin receptor type 1 |
---|
Ligand | BDBM50051568 |
---|
Substrate/Competitor | n/a |
---|
Ki | >10000±n/a nM |
---|
Comments | PDSP_1701 |
---|
Citation | Siehler, S; Seuwen, K; Hoyer, D Characterisation of human recombinant somatostatin receptors. 1. Radioligand binding studies. Naunyn Schmiedebergs Arch Pharmacol360:488-99 (1999) [PubMed] Article |
---|
More Info.: | Get all data from this article |
---|
|
Somatostatin receptor type 1 |
---|
Name: | Somatostatin receptor type 1 |
Synonyms: | SOMATOSTATIN SST1 | SRIF-2 | SS-1-R | SS1-R | SS1R | SSR1_HUMAN | SSTR1 | Somatostatin receptor type 1 (SSTR1) |
Type: | Enzyme |
Mol. Mass.: | 42692.81 |
Organism: | Homo sapiens (Human) |
Description: | P30872 |
Residue: | 391 |
Sequence: | MFPNGTASSPSSSPSPSPGSCGEGGGSRGPGAGAADGMEEPGRNASQNGTLSEGQGSAIL
ISFIYSVVCLVGLCGNSMVIYVILRYAKMKTATNIYILNLAIADELLMLSVPFLVTSTLL
RHWPFGALLCRLVLSVDAVNMFTSIYCLTVLSVDRYVAVVHPIKAARYRRPTVAKVVNLG
VWVLSLLVILPIVVFSRTAANSDGTVACNMLMPEPAQRWLVGFVLYTFLMGFLLPVGAIC
LCYVLIIAKMRMVALKAGWQQRKRSERKITLMVMMVVMVFVICWMPFYVVQLVNVFAEQD
DATVSQLSVILGYANSCANPILYGFLSDNFKRSFQRILCLSWMDNAAEEPVDYYATALKS
RAYSVEDFQPENLESGGVFRNGTCTSRITTL
|
|
|
BDBM50051568 |
---|
n/a |
---|
Name | BDBM50051568 |
Synonyms: | (3S,6S,9S,12R,15S,18S)-9-(4-Amino-butyl)-3-benzyl-15-(4-hydroxy-benzyl)-12-(1H-indol-3-ylmethyl)-6-isopropyl-1,18-dimethyl-1,4,7,10,13,16hexaaza-cyclooctadecane-2,5,8,11,14,17-hexaone | CHEMBL311695 | seglitide |
Type | Small organic molecule |
Emp. Form. | C44H56N8O7 |
Mol. Mass. | 808.9648 |
SMILES | CC(C)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](C)N(C)C(=O)[C@H](Cc2ccccc2)NC1=O |
Structure |
|