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Target5-hydroxytryptamine receptor 2C
LigandBDBM85530
Substrate/Competitorn/a
Ki 56±n/a nM
CommentsPDSP_1353
Citation Fitzgerald, LWBurn, TCBrown, BSPatterson, JPCorjay, MHValentine, PASun, JHLink, JRAbbaszade, IHollis, JMLargent, BLHartig, PRHollis, GFMeunier, PCRobichaud, AJRobertson, DW Possible role of valvular serotonin 5-HT(2B) receptors in the cardiopathy associated with fenfluramine. Mol Pharmacol57:75-81 (2000) [PubMed]
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5-hydroxytryptamine receptor 2C
Name:5-hydroxytryptamine receptor 2C
Synonyms:5-HT-2C | 5-HT2C | 5-HT2C-INI | 5-HT2c VGI | 5-HTR2C | 5-hydroxytryptamine receptor 1C | 5-hydroxytryptamine receptor 2C (5-HT-2C) | 5-hydroxytryptamine receptor 2C (5HT-2C) | 5HT-1C | 5HT2C_HUMAN | HTR1C | HTR2C | Serotonin (5-HT3) receptor | Serotonin 2c (5-HT2c) receptor | Serotonin Receptor 2C
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:51836.79
Organism:Homo sapiens (Human)
Description:P28335
Residue:458
Sequence:
MVNLRNAVHSFLVHLIGLLVWQCDISVSPVAAIVTDIFNTSDGGRFKFPDGVQNWPALSI
VIIIIMTIGGNILVIMAVSMEKKLHNATNYFLMSLAIADMLVGLLVMPLSLLAILYDYVW
PLPRYLCPVWISLDVLFSTASIMHLCAISLDRYVAIRNPIEHSRFNSRTKAIMKIAIVWA
ISIGVSVPIPVIGLRDEEKVFVNNTTCVLNDPNFVLIGSFVAFFIPLTIMVITYCLTIYV
LRRQALMLLHGHTEEPPGLSLDFLKCCKRNTAEEENSANPNQDQNARRRKKKERRPRGTM
QAINNERKASKVLGIVFFVFLIMWCPFFITNILSVLCEKSCNQKLMEKLLNVFVWIGYVC
SGINPLVYTLFNKIYRRAFSNYLRCNYKVEKKPPVRQIPRVAATALSGRELNVNIYRHTN
EPVIEKASDNEPGIEMQVENLELPVNPSSVVSERISSV
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  Blast E-value cutoff:
BDBM85530
n/a
NameBDBM85530
Synonyms:Nor-d-fenfluramine | Nor-dexfenfluramine | Norfenfluramine | Norfenfluramine (+) | Norfenfluramine (-) | d-Norfenfluramine
TypeSmall organic molecule
Emp. Form.C10H12F3N
Mol. Mass.203.2042
SMILESC[C@H](N)Cc1cccc(c1)C(F)(F)F
Structure
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