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TargetProstaglandin E2 receptor EP1 subtype
LigandBDBM50101824
Substrate/Competitorn/a
Ki>10000±n/a nM
CommentsPDSP_4306
Citation Abramovitz, MAdam, MBoie, YCarrière, MDenis, DGodbout, CLamontagne, SRochette, CSawyer, NTremblay, NMBelley, MGallant, MDufresne, CGareau, YRuel, RJuteau, HLabelle, MOuimet, NMetters, KM The utilization of recombinant prostanoid receptors to determine the affinities and selectivities of prostaglandins and related analogs. Biochim Biophys Acta1483:285-93 (2000) [PubMed]  Article
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Prostaglandin E2 receptor EP1 subtype
Name:Prostaglandin E2 receptor EP1 subtype
Synonyms:PE2R1_HUMAN | PGE receptor, EP1 subtype | PTGER1 | Prostaglandin E2 receptor | Prostaglandin E2 receptor EP1 subtype | Prostaglandin E2 receptor EP1 subtype (EP1) | Prostanoid EP1 receptor
Type:Enzyme
Mol. Mass.:41834.57
Organism:Homo sapiens (Human)
Description:P34995
Residue:402
Sequence:
MSPCGPLNLSLAGEATTCAAPWVPNTSAVPPSGASPALPIFSMTLGAVSNLLALALLAQA
AGRLRRRRSAATFLLFVASLLATDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFF
GLCPLLLGCGMAVERCVGVTRPLLHAARVSVARARLALAAVAAVALAVALLPLARVGRYE
LQYPGTWCFIGLGPPGGWRQALLAGLFASLGLVALLAALVCNTLSGLALLRARWRRRSRR
PPPASGPDSRRRWGAHGPRSASASSASSIASASTFFGGSRSSGSARRARAHDVEMVGQLV
GIMVVSCICWSPMLVLVALAVGGWSSTSLQRPLFLAVRLASWNQILDPWVYILLRQAVLR
QLLRLLPPRAGAKGGPAGLGLTPSAWEASSLRSSRHSGLSHF
Blast this sequence in BindingDB or PDB
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BDBM50101824
n/a
NameBDBM50101824
Synonyms:7-{(1R,3R)-3-Hydroxy-2-[(E)-(S)-4-hydroxy-4-(1-propyl-cyclobutyl)-but-1-enyl]-5-oxo-cyclopentyl}-heptanoic acid methyl ester | BUTAPROST | Butaprost (Methyl Ester) | CHEMBL432522
TypeSmall organic molecule
Emp. Form.C24H40O5
Mol. Mass.408.5714
SMILESCCCC1(CCC1)[C@@H](O)C\C=C\C1[C@H](O)CC(=O)[C@@H]1CCCCCCC(=O)OC
Structure
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