| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Prostaglandin F2-alpha receptor |
|---|
| Ligand | BDBM35847 |
|---|
| Substrate/Competitor | n/a |
|---|
| Ki | 119±n/a nM |
|---|
| Comments | PDSP_1462 |
|---|
| Citation |  Abramovitz, M; Adam, M; Boie, Y; Carrière, M; Denis, D; Godbout, C; Lamontagne, S; Rochette, C; Sawyer, N; Tremblay, NM; Belley, M; Gallant, M; Dufresne, C; Gareau, Y; Ruel, R; Juteau, H; Labelle, M; Ouimet, N; Metters, KM The utilization of recombinant prostanoid receptors to determine the affinities and selectivities of prostaglandins and related analogs. Biochim Biophys Acta1483:285-93 (2000) [PubMed] Article |
|---|
| More Info.: | Get all data from this article |
|---|
| |
| Prostaglandin F2-alpha receptor |
|---|
| Name: | Prostaglandin F2-alpha receptor |
|---|
| Synonyms: | PF2R_HUMAN | PGF receptor | PGF2 alpha receptor | PGF2-alpha receptor | PTGFR | Prostaglandin F | Prostanoid FP receptor |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 40072.29 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P43088 |
|---|
| Residue: | 359 |
|---|
| Sequence: | MSMNNSKQLVSPAAALLSNTTCQTENRLSVFFSVIFMTVGILSNSLAIAILMKAYQRFRQ
KSKASFLLLASGLVITDFFGHLINGAIAVFVYASDKEWIRFDQSNVLCSIFGICMVFSGL
CPLLLGSVMAIERCIGVTKPIFHSTKITSKHVKMMLSGVCLFAVFIALLPILGHRDYKIQ
ASRTWCFYNTEDIKDWEDRFYLLLFSFLGLLALGVSLLCNAITGITLLRVKFKSQQHRQG
RSHHLEMVIQLLAIMCVSCICWSPFLVTMANIGINGNHSLETCETTLFALRMATWNQILD
PWVYILLRKAVLKNLYKLASQCCGVHVISLHIWELSSIKNSLKVAAISESPVAEKSAST
|
|
|
|---|
| BDBM35847 |
|---|
| n/a |
|---|
| Name | BDBM35847 |
|---|
| Synonyms: | (15S)-prostaglandin E2 | (5Z,11alpha,13E,15S)-11,15-dihydroxy-9-oxoprosta-5,13-dien-1-oic acid | (5Z,13E,15S)-11alpha,15-dihydroxy-9-oxoprosta-5,13-dien-1-oic acid | (E,Z)-(1R,2R,3R)-7-(3-Hydroxy-2-((3S)-(3-hydroxy-1-octenyl))-5-oxocyclopentyl)-5-heptenoic acid | CHEMBL548 | DINOPROSTONE | PGE2 | [3H]Dinoprostone | [3H]PGE2 | [3H]Prostaglandin E2 | prostaglandin E2 |
|---|
| Type | radiolabeled ligand |
|---|
| Emp. Form. | C20H32O5 |
|---|
| Mol. Mass. | 352.4651 |
|---|
| SMILES | CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1C\C=C/CCCC(O)=O |
|---|
| Structure | 
|
|---|
Search and Browse
