| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 1E |
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| Ligand | BDBM50098551 |
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| Substrate/Competitor | n/a |
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| Ki | 6309.57±n/a nM |
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| Comments | PDSP_3688 |
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| Citation |  Lovell, PJ; Bromidge, SM; Dabbs, S; Duckworth, DM; Forbes, IT; Jennings, AJ; King, FD; Middlemiss, DN; Rahman, SK; Saunders, DV; Collin, LL; Hagan, JJ; Riley, GJ; Thomas, DR A novel, potent, and selective 5-HT(7) antagonist: (R)-3-(2-(2-(4-methylpiperidin-1-yl)ethyl)pyrrolidine-1-sulfonyl) phen ol (SB-269970). J Med Chem43:342-5 (2000) [PubMed] Article |
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| More Info.: | Get all data from this article |
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| 5-hydroxytryptamine receptor 1E |
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| Name: | 5-hydroxytryptamine receptor 1E |
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| Synonyms: | 5-HT-1E | 5-HT1E | 5-Hydroxytryptamine Receptor Subtype 1E (5HT1E) | 5-hydroxytryptamine receptor 1E | 5-hydroxytryptamine receptor 1E (5-HT-1E) (S31) | 5-hydroxytryptamine receptor 1E (5-HT-1E) (Serotonin receptor 1E) (5-HT1E) (S31). | 5HT1E_HUMAN | HTR1E | S31 | Serotonin (5-HT) receptor | Serotonin 1e (5-HT1e) receptor | Serotonin Receptor 1E |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 41697.80 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_112822 |
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| Residue: | 365 |
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| Sequence: | MNITNCTTEASMAIRPKTITEKMLICMTLVVITTLTTLLNLAVIMAIGTTKKLHQPANYL
ICSLAVTDLLVAVLVMPLSIIYIVMDRWKLGYFLCEVWLSVDMTCCTCSILHLCVIALDR
YWAITNAIEYARKRTAKRAALMILTVWTISIFISMPPLFWRSHRRLSPPPSQCTIQHDHV
IYTIYSTLGAFYIPLTLILILYYRIYHAAKSLYQKRGSSRHLSNRSTDSQNSFASCKLTQ
TFCVSDFSTSDPTTEFEKFHASIRIPPFDNDLDHPGERQQISSTRERKAARILGLILGAF
ILSWLPFFIKELIVGLSIYTVSSEVADFLTWLGYVNSLINPLLYTSFNEDFKLAFKKLIR
CREHT
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| BDBM50098551 |
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| n/a |
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| Name | BDBM50098551 |
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| Synonyms: | (R)-3-(2-(2-(4-methylpiperidin-1-yl)ethyl)pyrrolidin-1-ylsulfonyl)phenol | (R)-3-(2-(2-(4-methylpiperidin-1-yl)ethyl)pyrrolidine-1-sulfonyl)phenol | 3-{(R)-2-[2-(4-Methyl-piperidin-1-yl)-ethyl]-pyrrolidine-1-sulfonyl}-phenol | 3-{(S)-2-[2-(4-Methyl-piperidin-1-yl)-ethyl]-pyrrolidine-1-sulfonyl}-phenol | 3-{2-[2-(4-Methyl-piperidin-1-yl)-ethyl]-pyrrolidine-1-sulfonyl}-phenol | 3-{2-[2-(4-Methyl-piperidin-1-yl)-ethyl]-pyrrolidine-1-sulfonyl}-phenol (SB-269970) | CHEMBL282199 | SB-269970 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H28N2O3S |
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| Mol. Mass. | 352.492 |
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| SMILES | CC1CCN(CC[C@H]2CCCN2S(=O)(=O)c2cccc(O)c2)CC1 |r| |
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| Structure | 
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