| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Solute carrier organic anion transporter family member 2A1 |
|---|
| Ligand | BDBM50020300 |
|---|
| Substrate/Competitor | n/a |
|---|
| Ki | 45±n/a nM |
|---|
| Comments | PDSP_1467 |
|---|
| Citation |  Schuster, VL; Itoh, S; Andrews, SW; Burk, RM; Chen, J; Kedzie, KM; Gil, DW; Woodward, DF Synthetic modification of prostaglandin f(2alpha) indicates different structural determinants for binding to the prostaglandin F receptor versus the prostaglandin transporter. Mol Pharmacol58:1511-6 (2000) [PubMed] Article |
|---|
| More Info.: | Get all data from this article |
|---|
| |
| Solute carrier organic anion transporter family member 2A1 |
|---|
| Name: | Solute carrier organic anion transporter family member 2A1 |
|---|
| Synonyms: | OATP2A1 | Prostaglandin Transporter | SLC21A2 | SLCO2A1 | SO2A1_HUMAN |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 70068.67 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Prostaglandin Transporter 0 HUMAN::Q92959 |
|---|
| Residue: | 643 |
|---|
| Sequence: | MGLLPKLGASQGSDTSTSRAGRCARSVFGNIKVFVLCQGLLQLCQLLYSAYFKSSLTTIE
KRFGLSSSSSGLISSLNEISNAILIIFVSYFGSRVHRPRLIGIGGLFLAAGAFILTLPHF
LSEPYQYTLASTGNNSRLQAELCQKHWQDLPPSKCHSTTQNPQKETSSMWGLMVVAQLLA
GIGTVPIQPFGISYVDDFSEPSNSPLYISILFAISVFGPAFGYLLGSVMLQIFVDYGRVN
TAAVNLVPGDPRWIGAWWLGLLISSALLVLTSFPFFFFPRAMPIGAKRAPATADEARKLE
EAKSRGSLVDFIKRFPCIFLRLLMNSLFVLVVLAQCTFSSVIAGLSTFLNKFLEKQYGTS
AAYANFLIGAVNLPAAALGMLFGGILMKRFVFSLQAIPRIATTIITISMILCVPLFFMGC
STPTVAEVYPPSTSSSIHPQSPACRRDCSCPDSIFHPVCGDNGIEYLSPCHAGCSNINMS
SATSKQLIYLNCSCVTGGSASAKTGSCPVPCAHFLLPAIFLISFVSLIACISHNPLYMMV
LRVVNQEEKSFAIGVQFLLMRLLAWLPSPALYGLTIDHSCIRWNSLCLGRRGACAYYDND
ALRDRYLGLQMGYKALGMLLLCFISWRVKKNKEYNVQKAAGLI
|
|
|
|---|
| BDBM50020300 |
|---|
| n/a |
|---|
| Name | BDBM50020300 |
|---|
| Synonyms: | (S-isomer)7-[3,5-Dihydroxy-2-(3-hydroxy-oct-1-enyl)-cyclopentyl]-hept-5-enoic acid | (Z)-7-[(1R,3R,5S)-3,5-Dihydroxy-2-((E)-(S)-3-hydroxy-oct-1-enyl)-cyclopentyl]-hept-5-enoic acid | 7-[3,5-Dihydroxy-2-(3-hydroxy-oct-1-enyl)-cyclopentyl]-hept-5-enoic acid | CHEMBL12114 | PGF2Alpha | Prostaglandin F2alpha7-[3,5-Dihydroxy-2-(3-hydroxy-oct-1-enyl)-cyclopentyl]-hept-5-enoic acid |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C20H34O5 |
|---|
| Mol. Mass. | 354.481 |
|---|
| SMILES | CCCCC[C@H](O)\C=C\C1[C@H](O)C[C@H](O)[C@@H]1C\C=C/CCCC(O)=O |
|---|
| Structure | 
|
|---|
Search and Browse
