Ki Summary

Reaction Details

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Target

Solute carrier organic anion transporter family member 2A1

Ligand

BDBM85339

Substrate/Competitor

n/a

168±n/a nM

Comments

PDSP_1469

Citation

Schuster, VL; Itoh, S; Andrews, SW; Burk, RM; Chen, J; Kedzie, KM; Gil, DW; Woodward, DF Synthetic modification of prostaglandin f(2alpha) indicates different structural determinants for binding to the prostaglandin F receptor versus the prostaglandin transporter. Mol Pharmacol58:1511-6 (2000) [PubMed] Article

More Info.:

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Solute carrier organic anion transporter family member 2A1

Name:

Solute carrier organic anion transporter family member 2A1

Synonyms:

OATP2A1 | Prostaglandin Transporter | SLC21A2 | SLCO2A1 | SO2A1_HUMAN

Type:

Enzyme Catalytic Domain

Mol. Mass.:

70068.67

Organism:

Homo sapiens (Human)

Description:

Prostaglandin Transporter 0 HUMAN::Q92959

Residue:

643

Sequence:

MGLLPKLGASQGSDTSTSRAGRCARSVFGNIKVFVLCQGLLQLCQLLYSAYFKSSLTTIE
KRFGLSSSSSGLISSLNEISNAILIIFVSYFGSRVHRPRLIGIGGLFLAAGAFILTLPHF
LSEPYQYTLASTGNNSRLQAELCQKHWQDLPPSKCHSTTQNPQKETSSMWGLMVVAQLLA
GIGTVPIQPFGISYVDDFSEPSNSPLYISILFAISVFGPAFGYLLGSVMLQIFVDYGRVN
TAAVNLVPGDPRWIGAWWLGLLISSALLVLTSFPFFFFPRAMPIGAKRAPATADEARKLE
EAKSRGSLVDFIKRFPCIFLRLLMNSLFVLVVLAQCTFSSVIAGLSTFLNKFLEKQYGTS
AAYANFLIGAVNLPAAALGMLFGGILMKRFVFSLQAIPRIATTIITISMILCVPLFFMGC
STPTVAEVYPPSTSSSIHPQSPACRRDCSCPDSIFHPVCGDNGIEYLSPCHAGCSNINMS
SATSKQLIYLNCSCVTGGSASAKTGSCPVPCAHFLLPAIFLISFVSLIACISHNPLYMMV
LRVVNQEEKSFAIGVQFLLMRLLAWLPSPALYGLTIDHSCIRWNSLCLGRRGACAYYDND
ALRDRYLGLQMGYKALGMLLLCFISWRVKKNKEYNVQKAAGLI

BDBM85339

n/a

Name

BDBM85339

Synonyms:

17-PHENYL TRINOR PGF2ALPHA-IPR | CAS_130209-76-6 | PGF2Alpha,17-phenyl

Type

Small organic molecule

Emp. Form.

C26H38O5

Mol. Mass.

430.5769

SMILES

CC(C)OC(=O)CCC\C=C/C[C@H]1[C@@H](O)C[C@@H](O)[C@@H]1\C=C\[C@@H](O)CCc1ccccc1 |r|

Structure