| Reaction Details |
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 | Report a problem with these data |
| Target | Histamine receptor H4 |
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| Ligand | BDBM7966 |
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| Substrate/Competitor | n/a |
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| Ki | 104±n/a nM |
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| Comments | PDSP_934 |
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| Citation |  Zhu, Y; Michalovich, D; Wu, H; Tan, KB; Dytko, GM; Mannan, IJ; Boyce, R; Alston, J; Tierney, LA; Li, X; Herrity, NC; Vawter, L; Sarau, HM; Ames, RS; Davenport, CM; Hieble, JP; Wilson, S; Bergsma, DJ; Fitzgerald, LR Cloning, expression, and pharmacological characterization of a novel human histamine receptor. Mol Pharmacol59:434-41 (2001) [PubMed] Article |
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| More Info.: | Get all data from this article |
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| Histamine receptor H4 |
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| Name: | Histamine receptor H4 |
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| Synonyms: | HISTAMINE H4 | HRH4 | Histamine H4 receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 44536.99 |
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| Organism: | GUINEA PIG |
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| Description: | HISTAMINE H4 HRH4 GUINEA PIG::Q91ZY3 |
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| Residue: | 389 |
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| Sequence: | MLANNSTIALTSIKISLTFLMSLLAIAIMLGNVVVILAFIVDRNLRHRSNYFFLNLAIAD
FFVGAIAIPLYIPSSLTYWTSGKQACVFWLITDYLLCTASVYNIVLISYDRYQSVSNAVW
YRAQHSGTWKIATQMVAVWIFSFMTNGPMILISDSWQNSTTECEPGFLKKWYFALPTSLL
EFLIPILLVAYFSAHIYWSLWKREKLSRCLSHPVLPSDSSSSDHGHSCRQDPDSRATLPA
RKETTASLGSDKSRRKSSLLFSIRAYKNSNVIASKMGFLSHSDSLALQQREHIELFRARK
LAKSLAILLAAFAICWAPYSLTTVIYSFFPERNLTKSTWYHTAFWLQWFNSFVNPFLYPL
CHKRFQKAFLKILPVRRQSTPPHNRSIST
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| BDBM7966 |
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| n/a |
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| Name | BDBM7966 |
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| Synonyms: | 2-(1H-imidazol-4-yl)ethan-1-amine | CHEMBL544208 | CHEMBL90 | Ceplene | Ergotidine | HISTAMINE DIHYDROCHLORIDE | Histamine | L-histamine | Peremin | [3H]histamine |
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| Type | Small organic molecule |
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| Emp. Form. | C5H9N3 |
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| Mol. Mass. | 111.1451 |
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| SMILES | NCCc1cnc[nH]1 |
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| Structure | 
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