| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 4 |
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| Ligand | BDBM50122872 |
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| Substrate/Competitor | n/a |
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| Ki | 8±n/a nM |
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| Comments | PDSP_1544 |
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| Citation |  Briejer, MR; Bosmans, JP; Van Daele, P; Jurzak, M; Heylen, L; Leysen, JE; Prins, NH; Schuurkes, JA The in vitro pharmacological profile of prucalopride, a novel enterokinetic compound. Eur J Pharmacol423:71-83 (2001) [PubMed] Article |
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| More Info.: | Get all data from this article |
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| 5-hydroxytryptamine receptor 4 |
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| Name: | 5-hydroxytryptamine receptor 4 |
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| Synonyms: | 5-HT-4 | 5-HT4 | 5-HT4S | 5-HT4a | 5-HT4b | 5-HT4c | 5-HT4d | 5-HT4hb | 5-hydroxytryptamine receptor 4 | 5-hydroxytryptamine receptor 4 (5-HT4) | 5HT4R_HUMAN | HTR4 | Serotonin (5-HT) receptor | Serotonin (5-HT3) receptor | Serotonin 4 (5-HT4) receptor | Serotonin Receptor 4 |
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| Type: | Enzyme |
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| Mol. Mass.: | 43767.54 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q13639 |
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| Residue: | 388 |
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| Sequence: | MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV
SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY
AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN
STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRP
QSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWL
GYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTHVLRD
AVECGGQWESQCHPPATSPLVAAQPSDT
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| BDBM50122872 |
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| n/a |
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| Name | BDBM50122872 |
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| Synonyms: | 4-Amino-5-chloro-2,3-dihydro-benzofuran-7-carboxylic acid [1-(3-methoxy-propyl)-piperidin-4-yl]-amide | CHEMBL117287 | PRUCALOPRIDE | US9663465, prucalopride |
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| Type | Small organic molecule |
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| Emp. Form. | C18H26ClN3O3 |
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| Mol. Mass. | 367.87 |
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| SMILES | COCCCN1CCC(CC1)NC(=O)c1cc(Cl)c(N)c2CCOc12 |
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| Structure | 
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