| Reaction Details |
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 | Report a problem with these data |
| Target | Vasoactive intestinal polypeptide receptor 1 |
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| Ligand | BDBM50122872 |
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| Substrate/Competitor | n/a |
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| Ki | >10000±n/a nM |
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| Comments | PDSP_1544 |
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| Citation |  Briejer, MR; Bosmans, JP; Van Daele, P; Jurzak, M; Heylen, L; Leysen, JE; Prins, NH; Schuurkes, JA The in vitro pharmacological profile of prucalopride, a novel enterokinetic compound. Eur J Pharmacol423:71-83 (2001) [PubMed] Article |
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| More Info.: | Get all data from this article |
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| Vasoactive intestinal polypeptide receptor 1 |
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| Name: | Vasoactive intestinal polypeptide receptor 1 |
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| Synonyms: | VIP 1 | VIPR1 | VIPR1_HUMAN | Vasoactive intestinal polypeptide receptor 1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 51557.18 |
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| Organism: | Homo sapiens (Human) |
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| Description: | VIP 1 VIPR1 0::P32241 |
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| Residue: | 457 |
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| Sequence: | MRPPSPLPARWLCVLAGALAWALGPAGGQAARLQEECDYVQMIEVQHKQCLEEAQLENET
IGCSKMWDNLTCWPATPRGQVVVLACPLIFKLFSSIQGRNVSRSCTDEGWTHLEPGPYPI
ACGLDDKAASLDEQQTMFYGSVKTGYTIGYGLSLATLLVATAILSLFRKLHCTRNYIHMH
LFISFILRAAAVFIKDLALFDSGESDQCSEGSVGCKAAMVFFQYCVMANFFWLLVEGLYL
YTLLAVSFFSERKYFWGYILIGWGVPSTFTMVWTIARIHFEDYGCWDTINSSLWWIIKGP
ILTSILVNFILFICIIRILLQKLRPPDIRKSDSSPYSRLARSTLLLIPLFGVHYIMFAFF
PDNFKPEVKMVFELVVGSFQGFVVAILYCFLNGEVQAELRRKWRRWHLQGVLGWNPKYRH
PSGGSNGATCSTQVSMLTRVSPGARRSSSFQAEVSLV
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| BDBM50122872 |
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| n/a |
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| Name | BDBM50122872 |
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| Synonyms: | 4-Amino-5-chloro-2,3-dihydro-benzofuran-7-carboxylic acid [1-(3-methoxy-propyl)-piperidin-4-yl]-amide | CHEMBL117287 | PRUCALOPRIDE | US9663465, prucalopride |
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| Type | Small organic molecule |
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| Emp. Form. | C18H26ClN3O3 |
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| Mol. Mass. | 367.87 |
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| SMILES | COCCCN1CCC(CC1)NC(=O)c1cc(Cl)c(N)c2CCOc12 |
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| Structure | 
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