Reaction Details |
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Target | Prostaglandin-H2 D-isomerase |
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Ligand | BDBM50008805 |
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Substrate/Competitor | n/a |
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Ki | 0.34±n/a nM |
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Comments | PDSP_2289 |
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Citation | Arimura, A; Yasui, K; Kishino, J; Asanuma, F; Hasegawa, H; Kakudo, S; Ohtani, M; Arita, H Prevention of allergic inflammation by a novel prostaglandin receptor antagonist, S-5751. J Pharmacol Exp Ther298:411-9 (2001) [PubMed] |
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More Info.: | Get all data from this article |
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Prostaglandin-H2 D-isomerase |
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Name: | Prostaglandin-H2 D-isomerase |
Synonyms: | PDS | PGD2 | PTGDS | PTGDS_HUMAN |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 21031.11 |
Organism: | Homo sapiens (Human) |
Description: | PGD2 0 HUMAN::P41222 |
Residue: | 190 |
Sequence: | MATHHTLWMGLALLGVLGDLQAAPEAQVSVQPNFQQDKFLGRWFSAGLASNSSWLREKKA
ALSMCKSVVAPATDGGLNLTSTFLRKNQCETRTMLLQPAGSLGSYSYRSPHWGSTYSVSV
VETDYDQYALLYSQGSKGPGEDFRMATLYSRTQTPRAELKEKFTAFCKAQGFTEDTIVFL
PQTDKCMTEQ
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BDBM50008805 |
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n/a |
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Name | BDBM50008805 |
Synonyms: | 7-(3-Benzenesulfonylamino-bicyclo[2.2.1]hept-2-yl)-hept-5-enoic acid | CHEMBL56941 | S 145 | S-145,(+) |
Type | Small organic molecule |
Emp. Form. | C20H27NO4S |
Mol. Mass. | 377.498 |
SMILES | OC(=O)CCC\C=C/C[C@H]1[C@@H]2CCC(C2)C1NS(=O)(=O)c1ccccc1 |
Structure |
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