| Reaction Details |
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 | Report a problem with these data |
| Target | Trace amine-associated receptor 1 |
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| Ligand | BDBM22872 |
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| Substrate/Competitor | n/a |
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| Ki | 493±n/a nM |
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| Comments | PDSP_1402 |
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| Citation |  Borowsky, B; Adham, N; Jones, KA; Raddatz, R; Artymyshyn, R; Ogozalek, KL; Durkin, MM; Lakhlani, PP; Bonini, JA; Pathirana, S; Boyle, N; Pu, X; Kouranova, E; Lichtblau, H; Ochoa, FY; Branchek, TA; Gerald, C Trace amines: identification of a family of mammalian G protein-coupled receptors. Proc Natl Acad Sci U S A98:8966-71 (2001) [PubMed] Article |
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| More Info.: | Get all data from this article |
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| Trace amine-associated receptor 1 |
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| Name: | Trace amine-associated receptor 1 |
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| Synonyms: | TA1 | TAAR1 | TAAR1_HUMAN | TAR1 | TRAR1 | trace amine-associated receptor 1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 39107.47 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_792734 |
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| Residue: | 339 |
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| Sequence: | MMPFCHNIINISCVKNNWSNDVRASLYSLMVLIILTTLVGNLIVIVSISHFKQLHTPTNW
LIHSMATVDFLLGCLVMPYSMVRSAEHCWYFGEVFCKIHTSTDIMLSSASIFHLSFISID
RYYAVCDPLRYKAKMNILVICVMIFISWSVPAVFAFGMIFLELNFKGAEEIYYKHVHCRG
GCSVFFSKISGVLTFMTSFYIPGSIMLCVYYRIYLIAKEQARLISDANQKLQIGLEMKNG
ISQSKERKAVKTLGIVMGVFLICWCPFFICTVMDPFLHYIIPPTLNDVLIWFGYLNSTFN
PMVYAFFYPWFRKALKMMLFGKIFQKDSSRCKLFLELSS
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| BDBM22872 |
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| n/a |
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| Name | BDBM22872 |
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| Synonyms: | 1-(3-chloro-5,6-dihydrobenzo[b][1]benzothiepin-5-yl)-4-methyl-piperazine;maleate | 1-(8-chloro-10,11-dihydrodibenzo[b,f]thiepin-10-yl)-4-methylpiperazine | 1-{6-chloro-2-thiatricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3(8),4,6,11,13-hexaen-9-yl}-4-methylpiperazine | CHEMBL64249 | CLOROTEPINE (+) | CLOROTEPINE(-) | Clothepin | OCTOCLOTHEPIN,(+) | OCTOCLOTHEPIN,(-) | Octoclothepin | Octoclothepine |
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| Type | Small organic molecule |
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| Emp. Form. | C19H21ClN2S |
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| Mol. Mass. | 344.901 |
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| SMILES | CN1CCN(CC1)C1Cc2ccccc2Sc2ccc(Cl)cc12 |
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| Structure | 
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