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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Muscarinic acetylcholine receptor M4 | ||
| Ligand | BDBM85817 | ||
| Substrate/Competitor | n/a | ||
| Ki | 2.57±n/a nM | ||
| Comments | PDSP_2071 | ||
| Citation |  Christopoulos, A; Grant, MK; Ayoubzadeh, N; Kim, ON; Sauerberg, P; Jeppesen, L; El-Fakahany, EE Synthesis and pharmacological evaluation of dimeric muscarinic acetylcholine receptor agonists. J Pharmacol Exp Ther298:1260-8 (2001) [PubMed] | ||
| More Info.: | Get all data from this article | ||
| Muscarinic acetylcholine receptor M4 | |||
| Name: | Muscarinic acetylcholine receptor M4 | ||
| Synonyms: | ACM4_HUMAN | CHRM4 | Cholinergic, muscarinic M4 | Muscarinic acetylcholine receptor | Muscarinic acetylcholine receptor M2 and M4 | ||
| Type: | Enzyme Catalytic Domain | ||
| Mol. Mass.: | 53079.31 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Cholinergic, muscarinic M4 CHRM4 HUMAN M3::P08173 | ||
| Residue: | 479 | ||
| Sequence: |
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| BDBM85817 | |||
| n/a | |||
| Name | BDBM85817 | ||
| Synonyms: | NNC 11-1585 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C30H32N6O2S2 | ||
| Mol. Mass. | 572.744 | ||
| SMILES | C(Oc1nsnc1C1CN2CCC1CC2)C#Cc1ccc(cc1)C#CCOc1nsnc1C1CN2CCC1CC2 |(2.45,.06,;3.22,1.4,;4.76,1.4,;5.39,2.81,;6.92,2.64,;7.24,1.14,;5.91,.37,;5.51,-1.12,;6.28,-2.45,;5.51,-3.79,;3.97,-3.79,;3.2,-2.45,;3.97,-1.12,;5.3,-1.89,;4.21,-2.98,;.91,.06,;-.63,.06,;-2.17,.06,;-2.94,-1.27,;-4.48,-1.27,;-5.25,.06,;-4.48,1.4,;-2.94,1.4,;-6.79,.06,;-8.33,.07,;-9.87,.06,;-10.64,1.4,;-12.18,1.4,;-12.8,2.81,;-14.33,2.64,;-14.66,1.14,;-13.32,.37,;-12.92,-1.12,;-13.69,-2.45,;-12.92,-3.79,;-11.38,-3.79,;-10.61,-2.45,;-11.38,-1.12,;-12.72,-1.89,;-11.63,-2.98,)| | ||
| Structure | 
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