| Reaction Details |
|---|
 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 3A |
|---|
| Ligand | BDBM85826 |
|---|
| Substrate/Competitor | n/a |
|---|
| Ki | 500±n/a nM |
|---|
| Comments | PDSP_2299 |
|---|
| Citation |  Rënyi, L; Evenden, JL; Fowler, CJ; Jerning, E; Kelder, D; Lake-Bakaar, D; Larsson, LG; Mohell, N; Sällemark, M; Ross, SB The pharmacological profile of (R)-3,4-dihydro-N-isopropyl-3-(N-isopropyl-N-propylamino)-2H-1-benzopyran-5-carboxamide, a selective 5-hydroxytryptamine(1A) receptor agonist. J Pharmacol Exp Ther299:883-93 (2001) [PubMed] |
|---|
| More Info.: | Get all data from this article |
|---|
| |
| 5-hydroxytryptamine receptor 3A |
|---|
| Name: | 5-hydroxytryptamine receptor 3A |
|---|
| Synonyms: | 5-HT3 | 5-hydroxytryptamine receptor 3A | 5HT3A_RAT | 5ht3 | Htr3 | Htr3a | Serotonin (5-HT) receptor | Zacopride site-R |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 55428.70 |
|---|
| Organism: | RAT |
|---|
| Description: | 5-HT3 HTR3A RAT::P35563 |
|---|
| Residue: | 483 |
|---|
| Sequence: | MPLCIPQVLLALFLSVLIAQGEGSRRRATQAHSTTQPALLRLSDHLLANYKKGVRPVRDW
RKPTLVSIDVIMYAILNVDEKNQVLTTYIWYRQFWTDEFLQWTPEDFDNVTKLSIPTDSI
WVPDILINEFVDVGKSPSIPYVYVHHQGEVQNYKPLQLVTACSLDIYNFPFDVQNCSLTF
TSWLHTIQDINISLWRTPEEVRSDKSIFINQGEWELLGVFTKFQEFSIETSNSYAEMKFY
VVIRRRPLFYAVSLLLPSIFLMVVDIVGFCLPPDSGERVSFKITLLLGYSVFLIIVSDTL
PATAIGTPLIGVYFVVCMALLVISLAETIFIVQLVHKQDLQRPVPDWLRHLVLDRIAWLL
CLGEQPMAHRPPATFQANKTDDCSAMGNHCSHVGSPQDLEKTSRSRDSPLPPPREASLAV
RGLLQELSSIRHSLEKRDEMREVARDWLRVGYVLDRLLFRIYLLAVLAYSITLVTLWSIW
HYS
|
|
|
|---|
| BDBM85826 |
|---|
| n/a |
|---|
| Name | BDBM85826 |
|---|
| Synonyms: | (R)-N-Isopropyl-3-[isopropyl(propyl)amino]-3,4-dihydro-2H-1-benzopyran-5-carboxamide | NAE-086 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C19H30N2O2 |
|---|
| Mol. Mass. | 318.4537 |
|---|
| SMILES | CCCN(C(C)C)[C@H]1COc2cccc(C(=O)NC(C)C)c2C1 |
|---|
| Structure | 
|
|---|
Search and Browse
