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TargetHRH3
LigandBDBM22541
Substrate/Competitorn/a
Ki 0.87±n/a nM
CommentsPDSP_539
Citation Wieland KBongers GYamamoto YHashimoto TYamatodani AMenge WMTimmerman HLovenberg TWLeurs R Constitutive activity of histamine h(3) receptors stably expressed in SK-N-MC cells: display of agonism and inverse agonism by H(3) antagonists. J Pharmacol Exp Ther 299:908-14 (2001) [PubMed]
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HRH3
Name:HRH3
Synonyms:HISTAMINE H3 | Hrh3 protein
Type:Enzyme Catalytic Domain
Mol. Mass.:37860.96
Organism:RAT
Description:Q5PPG3
Residue:344
Sequence:
MERAPPDGLMNASGTLAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFV
ADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCAS
SVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGG
SSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAG
PEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRGSKPSASSASLEKRMKMVSQSITQRF
RLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGRCIPDY
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  Blast E-value cutoff:
BDBM22541
n/a
NameBDBM22541
Synonyms:CLOBENPROPIT | Clobenpropit | N''-[(4-chlorophenyl)methyl]{[3-(1H-imidazol-5-yl)propyl]sulfanyl}methanimidamide | VUF 9153 | VUF-9153 | VUF9153
TypeSmall organic molecule
Emp. Form.C14H17ClN4S
Mol. Mass.308.83
SMILESNC(SCCCc1cnc[nH]1)=NCc1ccc(Cl)cc1 |w:11.12|
Structure
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