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Target5-hydroxytryptamine receptor 4
LigandBDBM84745
Substrate/Competitorn/a
Ki 1000±n/a nM
CommentsPDSP_763
Citation Bymaster, FPDreshfield-Ahmad, LJThrelkeld, PGShaw, JLThompson, LNelson, DLHemrick-Luecke, SKWong, DT Comparative affinity of duloxetine and venlafaxine for serotonin and norepinephrine transporters in vitro and in vivo, human serotonin receptor subtypes, and other neuronal receptors. Neuropsychopharmacology25:871-80 (2001) [PubMed]  Article
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5-hydroxytryptamine receptor 4
Name:5-hydroxytryptamine receptor 4
Synonyms:5-HT4 | 5-hydroxytryptamine receptor 4 | 5HT4R_CAVPO | HTR4 | Serotonin 4 (5-HT4) receptor
Type:Enzyme Catalytic Domain
Mol. Mass.:43735.29
Organism:GUINEA PIG
Description:5-HT4 HTR4 GUINEA PIG::O70528
Residue:388
Sequence:
MDKLDANVSSKEGFGSVEKVVLLTFLSAVILMAILGNLLVMVAVCRDRQLRKIKTNYFIV
SLAFADLLVSVLVMPFGAIELVQDIWVYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYY
AICCQPLVYRNKMTPLRIALMLGGCWVIPMFISFLPIMQGWNNIGIVDLIEKRKFNQNSN
STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHARQIQVLQRAGAPAEGRP
QPADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQLWTAFLWL
GYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTHVLRD
TVECGGQWESQCHPAASSPLVAAQPIDT
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  Blast E-value cutoff:
BDBM84745
n/a
NameBDBM84745
Synonyms:CAS_136434-34-9 | DULOXETINE | LY-248686 | LY248686 | USRE49340, Rank 5
TypeSmall organic molecule
Emp. Form.C18H19NOS
Mol. Mass.297.415
SMILESCNCC[C@H](Oc1cccc2ccccc12)c1cccs1 |r|
Structure
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