| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Acetylcholinesterase |
|---|
| Ligand | BDBM86021 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Enzyme Inhibition Assay |
|---|
| Temperature | 303.15±0 K |
|---|
| Ki | 1.100e+5± 1.5e+3 nM |
|---|
| Citation |  Atta-ur-Rahman, A; Khalid, A; Sultana, N; Ghayur, MN; Mesaik, MA; Khan, MR; Gilani, AH; Choudhary, MI New natural cholinesterase inhibiting and calcium channel blocking quinoline alkaloids. J Enzyme Inhib Med Chem21:703-10 (2006) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Acetylcholinesterase |
|---|
| Name: | Acetylcholinesterase |
|---|
| Synonyms: | 3.1.1.7 | ACES_TETCF | Acetylcholinesterase (AChE) | Acetylcholinesterase precursor | ache |
|---|
| Type: | n/a |
|---|
| Mol. Mass.: | 65900.74 |
|---|
| Organism: | Tetronarce californica (Pacific electric ray) (Torpedo californica) |
|---|
| Description: | P04058 |
|---|
| Residue: | 586 |
|---|
| Sequence: | MNLLVTSSLGVLLHLVVLCQADDHSELLVNTKSGKVMGTRVPVLSSHISAFLGIPFAEPP
VGNMRFRRPEPKKPWSGVWNASTYPNNCQQYVDEQFPGFSGSEMWNPNREMSEDCLYLNI
WVPSPRPKSTTVMVWIYGGGFYSGSSTLDVYNGKYLAYTEEVVLVSLSYRVGAFGFLALH
GSQEAPGNVGLLDQRMALQWVHDNIQFFGGDPKTVTIFGESAGGASVGMHILSPGSRDLF
RRAILQSGSPNCPWASVSVAEGRRRAVELGRNLNCNLNSDEELIHCLREKKPQELIDVEW
NVLPFDSIFRFSFVPVIDGEFFPTSLESMLNSGNFKKTQILLGVNKDEGSFFLLYGAPGF
SKDSESKISREDFMSGVKLSVPHANDLGLDAVTLQYTDWMDDNNGIKNRDGLDDIVGDHN
VICPLMHFVNKYTKFGNGTYLYFFNHRASNLVWPEWMGVIHGYEIEFVFGLPLVKELNYT
AEEEALSRRIMHYWATFAKTGNPNEPHSQESKWPLFTTKEQKFIDLNTEPMKVHQRLRVQ
MCVFWNQFLPKLLNATACDGELSSSGTSSSKGIIFYVLFSILYLIF
|
|
|
|---|
| BDBM86021 |
|---|
| n/a |
|---|
| Name | BDBM86021 |
|---|
| Synonyms: | 2,2,6-Trimethyl-3,4,5,6-tetrahydro-2H-pyrano[3,2-c]quinoline-5-one, 2 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C15H17NO3 |
|---|
| Mol. Mass. | 259.3004 |
|---|
| SMILES | Cn1c2ccccc2c2OC(C)(C)[C@@H](O)Cc2c1=O |r| |
|---|
| Structure | 
|
|---|
Search and Browse
