| Reaction Details |
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 | Report a problem with these data |
| Target | Histamine H1 receptor |
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| Ligand | BDBM50292411 |
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| Substrate/Competitor | n/a |
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| Ki | 0.93±n/a nM |
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| Comments | PDSP_1917 |
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| Citation |  Booth, RG; Moniri, NH; Bakker, RA; Choksi, NY; Nix, WB; Timmerman, H; Leurs, R A novel phenylaminotetralin radioligand reveals a subpopulation of histamine H(1) receptors. J Pharmacol Exp Ther302:328-36 (2002) [PubMed] Article |
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| More Info.: | Get all data from this article |
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| Histamine H1 receptor |
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| Name: | Histamine H1 receptor |
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| Synonyms: | HISTAMINE H1 | HRH1 | HRH1_CAVPO |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 55641.53 |
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| Organism: | Cavia porcellus (domestic guinea pig) |
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| Description: | Guinea pig cerebellum was used in binding assay. |
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| Residue: | 488 |
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| Sequence: | MSFLPGMTPVTLSNFSWALEDRMLEGNSTTTPTRQLMPLVVVLSSVSLVTVALNLLVLYA
VRSERKLHTVGNLYIVSLSVADLIVGAVVMPMSILYLHRSAWILGRPLCLFWLSMDYVAS
TASIFSVFILCIDRYRSVQQPLRYLRYRTKTRASATILGAWLLSFLWVIPILGWHHFMAP
TSEPREKKCETDFYDVTWFKVMTAIINFYLPTLLMLWFYIRIYKAVRRHCQHRQLINSSL
PSFSEMKLKLENAKVDTRRMGKESPWEDPKRCSKDASGVHTPMPSSQHLVDMPCAAVLSE
DEGGEVGTRQMPMLAVGDGRCCEALNHMHSQLELSGQSRATHSISARPEEWTVVDGQSFP
ITDSDTSTEAAPMGGQPRSGSNSGLDYIKFTWRRLRSHSRQYTSGLHLNRERKAAKQLGC
IMAAFILCWIPYFVFFMVIAFCKSCSNEPVHMFTIWLGYLNSTLNPLIYPLCNENFRKTF
KRILRIPP
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| BDBM50292411 |
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| n/a |
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| Name | BDBM50292411 |
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| Synonyms: | (E)-2-(3-(pyrrolidin-1-yl)-1-p-tolylprop-1-enyl)pyridine | 1-((E)-3-Pyridin-2-yl-3-p-tolyl-allyl)-pyrrolidinium | 2-((E)-3-Pyrrolidin-1-yl-1-p-tolyl-propenyl)-pyridine | 2-(3-(pyrrolidin-1-yl)-1-p-tolylprop-1-enyl)pyridine | 2-(3-Pyrrolidin-1-yl-1-p-tolyl-propenyl)-pyridine | Actahist | Actidil | Actifed | Allerfed | CHEMBL855 | Corphed | Histafed | Myfed | Myidyl | TRIPROLIDINE | Triacin-C | Trilitron | Triphed | Triprolidin |
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| Type | Small organic molecule |
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| Emp. Form. | C19H22N2 |
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| Mol. Mass. | 278.3914 |
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| SMILES | Cc1ccc(cc1)C(=C/CN1CCCC1)\c1ccccn1 |
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| Structure | 
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