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TargetHistamine H1 receptor
LigandBDBM50292411
Substrate/Competitorn/a
Ki 0.69±n/a nM
CommentsPDSP_1917
Citation Booth RGMoniri NHBakker RAChoksi NYNix WBTimmerman HLeurs R A novel phenylaminotetralin radioligand reveals a subpopulation of histamine H(1) receptors. J Pharmacol Exp Ther 302:328-36 (2002) [PubMed]  Article
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Histamine H1 receptor
Name:Histamine H1 receptor
Synonyms:HISTAMINE H1
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:55641.53
Organism:Cavia porcellus (domestic guinea pig)
Description:Guinea pig cerebellum was used in binding assay.
Residue:488
Sequence:
MSFLPGMTPVTLSNFSWALEDRMLEGNSTTTPTRQLMPLVVVLSSVSLVTVALNLLVLYA
VRSERKLHTVGNLYIVSLSVADLIVGAVVMPMSILYLHRSAWILGRPLCLFWLSMDYVAS
TASIFSVFILCIDRYRSVQQPLRYLRYRTKTRASATILGAWLLSFLWVIPILGWHHFMAP
TSEPREKKCETDFYDVTWFKVMTAIINFYLPTLLMLWFYIRIYKAVRRHCQHRQLINSSL
PSFSEMKLKLENAKVDTRRMGKESPWEDPKRCSKDASGVHTPMPSSQHLVDMPCAAVLSE
DEGGEVGTRQMPMLAVGDGRCCEALNHMHSQLELSGQSRATHSISARPEEWTVVDGQSFP
ITDSDTSTEAAPMGGQPRSGSNSGLDYIKFTWRRLRSHSRQYTSGLHLNRERKAAKQLGC
IMAAFILCWIPYFVFFMVIAFCKSCSNEPVHMFTIWLGYLNSTLNPLIYPLCNENFRKTF
KRILRIPP
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BDBM50292411
n/a
NameBDBM50292411
Synonyms:(E)-2-(3-(pyrrolidin-1-yl)-1-p-tolylprop-1-enyl)pyridine | 1-((E)-3-Pyridin-2-yl-3-p-tolyl-allyl)-pyrrolidinium | 2-((E)-3-Pyrrolidin-1-yl-1-p-tolyl-propenyl)-pyridine | 2-(3-(pyrrolidin-1-yl)-1-p-tolylprop-1-enyl)pyridine | 2-(3-Pyrrolidin-1-yl-1-p-tolyl-propenyl)-pyridine | Actahist | Actidil | Actifed | Allerfed | CHEMBL855 | Corphed | Histafed | Myfed | Myidyl | TRIPROLIDINE | Triacin-C | Trilitron | Triphed | Triprolidin
TypeSmall organic molecule
Emp. Form.C19H22N2
Mol. Mass.278.3914
SMILESCc1ccc(cc1)C(=C/CN1CCCC1)\c1ccccn1
Structure
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