Reaction Details | |||
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Target | Sodium-dependent dopamine transporter | ||
Ligand | BDBM50129952 | ||
Substrate/Competitor | n/a | ||
Ki | 877.4±n/a nM | ||
Comments | PDSP_3171 | ||
Citation | Butterweck, V; Nahrstedt, A; Evans, J; Hufeisen, S; Rauser, L; Savage, J; Popadak, B; Ernsberger, P; Roth, BL In vitro receptor screening of pure constituents of St. John's wort reveals novel interactions with a number of GPCRs. Psychopharmacology (Berl)162:193-202 (2002) [PubMed] Article | ||
More Info.: | Get all data from this article | ||
Sodium-dependent dopamine transporter | |||
Name: | Sodium-dependent dopamine transporter | ||
Synonyms: | Dopamine transporter | SC6A3_BOVIN | SLC6A3 | Sodium-dependent dopamine transporter | ||
Type: | Enzyme Catalytic Domain | ||
Mol. Mass.: | 75707.43 | ||
Organism: | BOVINE | ||
Description: | Dopamine Transporter SLC6A3 BOVINE::P27922 | ||
Residue: | 693 | ||
Sequence: |
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BDBM50129952 | |||
n/a | |||
Name | BDBM50129952 | ||
Synonyms: | 2-(3-(5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-8-yl)-4-hydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one | 8-[5-(5,7-Dihydroxy-4-oxo-4H-chromen-2-yl)-2-hydroxy-phenyl]-5,7-dihydroxy-2-(4-hydroxy-phenyl)-chromen-4-one | Amentoflavone | CHEMBL63354 | cid_5281600 | ||
Type | Small organic molecule | ||
Emp. Form. | C30H18O10 | ||
Mol. Mass. | 538.4579 | ||
SMILES | Oc1ccc(cc1)-c1cc(=O)c2c(O)cc(O)c(-c3cc(ccc3O)-c3cc(O)c4c(cc(O)cc4=O)o3)c2o1 |(13.25,-26.01,;14.59,-25.24,;14.59,-23.7,;15.92,-22.93,;17.26,-23.7,;17.26,-25.24,;15.93,-26.01,;18.58,-22.93,;19.91,-23.69,;21.23,-22.92,;22.57,-23.69,;21.22,-21.4,;22.56,-20.64,;23.88,-21.41,;22.55,-19.1,;21.22,-18.33,;21.22,-16.79,;19.9,-19.11,;18.57,-18.34,;17.23,-19.1,;15.9,-18.33,;15.9,-16.79,;17.23,-16.02,;18.57,-16.79,;19.91,-16.02,;14.57,-19.09,;14.56,-20.65,;13.21,-21.42,;13.21,-22.96,;11.87,-20.64,;11.88,-19.08,;10.54,-18.32,;9.21,-19.09,;7.87,-18.32,;9.21,-20.64,;10.54,-21.41,;10.54,-22.95,;13.22,-18.3,;19.9,-20.64,;18.58,-21.4,)| | ||
Structure |