| Reaction Details |
|---|
 | Report a problem with these data |
| Target | cholinergic receptor, nicotinic, alpha 1 (Muscle) isoform X1 |
|---|
| Ligand | BDBM86042 |
|---|
| Substrate/Competitor | n/a |
|---|
| Ki | 0.0031±n/a nM |
|---|
| Comments | PDSP_2905 |
|---|
| Citation |  Avalos, M; Parker, MJ; Maddox, FN; Carroll, FI; Luetje, CW Effects of pyridine ring substitutions on affinity, efficacy, and subtype selectivity of neuronal nicotinic receptor agonist epibatidine. J Pharmacol Exp Ther302:1246-52 (2002) [PubMed] Article |
|---|
| More Info.: | Get all data from this article |
|---|
| |
| cholinergic receptor, nicotinic, alpha 1 (Muscle) isoform X1 |
|---|
| Name: | cholinergic receptor, nicotinic, alpha 1 (Muscle) isoform X1 |
|---|
| Synonyms: | Cholinergic, Nicotinic Alpha3Beta2 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 51980.65 |
|---|
| Organism: | Xenopus |
|---|
| Description: | Cholinergic, Nicotinic Alpha3Beta2 0 Xenopus::F6RLM5 |
|---|
| Residue: | 457 |
|---|
| Sequence: | MDYTASCLIFFFIAAGPVFSSDHETRLIGDLFANYNKVVRPVETYKDQVVVTVGLQLIQL
INVDEVNQIVSTNIRLKQQWVDVNLKWDPAKYGGVKKLRIPSSEVWCPDLVLYNNADGDF
AISKDTKILLEHTGKITWTPPAIFKSYCEIIVTHFPFDQQNCSMKFGTWTYDGTLVVINP
DRDRPDLSNFMASGEWMMKDYRCWKHWVYYTCCPDKPYLDITYHFVLQRLPLYFIVNVII
PCLLFSFLTGLVFYLPTDSGEKMTLSISVLLSLTVFLLVIVELIPSTSSAVPLIGKYMLF
TMVFVIASIIITVIVINTHHRSPSTHTMPPWVRKIFIDTIPNIMFFSTMKRPSQEKQPQT
TFAEEMDISDISGKLGPAAVTYQSPALKNPDVKSAIEGIKYIAETMKSDQESNKASEEWK
FVAMVLDHILLAVFMTVCVIGTLAVFAGRIIEMNMQD
|
|
|
|---|
| BDBM86042 |
|---|
| n/a |
|---|
| Name | BDBM86042 |
|---|
| Synonyms: | NEP |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C11H14N2 |
|---|
| Mol. Mass. | 174.2423 |
|---|
| SMILES | C1CC2NC1C[C@@H]2c1cccnc1 |r,TLB:7:6:0.1:3| |
|---|
| Structure | 
|
|---|
Search and Browse
