Ki Summary

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Target

Vasoactive intestinal polypeptide receptor 1

Ligand

BDBM81828

Substrate/Competitor

n/a

0.2±n/a nM

Comments

PDSP_2122

Citation

Igarashi, H; Ito, T; Pradhan, TK; Mantey, SA; Hou, W; Coy, DH; Jensen, RT Elucidation of the vasoactive intestinal peptide pharmacophore for VPAC(2) receptors in human and rat and comparison to the pharmacophore for VPAC(1) receptors. J Pharmacol Exp Ther303:445-60 (2002) [PubMed] Article

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Vasoactive intestinal polypeptide receptor 1

Name:

Vasoactive intestinal polypeptide receptor 1

Synonyms:

VIP 1 | VIPR1 | VIPR1_HUMAN | Vasoactive intestinal polypeptide receptor 1

Type:

Enzyme Catalytic Domain

Mol. Mass.:

51557.18

Organism:

Homo sapiens (Human)

Description:

VIP 1 VIPR1 0::P32241

Residue:

457

Sequence:

MRPPSPLPARWLCVLAGALAWALGPAGGQAARLQEECDYVQMIEVQHKQCLEEAQLENET
IGCSKMWDNLTCWPATPRGQVVVLACPLIFKLFSSIQGRNVSRSCTDEGWTHLEPGPYPI
ACGLDDKAASLDEQQTMFYGSVKTGYTIGYGLSLATLLVATAILSLFRKLHCTRNYIHMH
LFISFILRAAAVFIKDLALFDSGESDQCSEGSVGCKAAMVFFQYCVMANFFWLLVEGLYL
YTLLAVSFFSERKYFWGYILIGWGVPSTFTMVWTIARIHFEDYGCWDTINSSLWWIIKGP
ILTSILVNFILFICIIRILLQKLRPPDIRKSDSSPYSRLARSTLLLIPLFGVHYIMFAFF
PDNFKPEVKMVFELVVGSFQGFVVAILYCFLNGEVQAELRRKWRRWHLQGVLGWNPKYRH
PSGGSNGATCSTQVSMLTRVSPGARRSSSFQAEVSLV

BDBM81828

n/a

Name

BDBM81828

Synonyms:

CAS_37221-79-7 | VIP(4-28) | Vasoactive intestinal polypeptide

Type

Small organic molecule

Emp. Form.

C147H237N43O43S

Mol. Mass.

3326.782

SMILES

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Structure