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TargetRetinol-binding protein 4
LigandBDBM249482
Substrate/Competitorn/a
Meas. Tech.TR-FRET Assay for Retinol-induced RBP4-TTR Interaction
pH7.5±n/a
IC50 4.33±n/a nM
Commentsextracted
Citation Petrukhin, KCioffi, CJohnson, GAllikmets, RFreeman, EChen, PConlon, MZhu, L Substituted 4-phenylpiperidines, their preparation and use US Patent US10072016 Publication Date 9/11/2018
More Info.:Get all data from this article,  Assay Method
 
Retinol-binding protein 4
Name:Retinol-binding protein 4
Synonyms:PRBP | Plasma retinol-binding protein | RBP | RBP4 | RET4_HUMAN | Retinol-binding protein 4 | Retinol-binding protein 4 (RBP4) | spa binding assay for rbp4
Type:Protein
Mol. Mass.:23008.75
Organism:Homo sapiens (Human)
Description:P02753
Residue:201
Sequence:
MKWVWALLLLAALGSGRAERDCRVSSFRVKENFDKARFSGTWYAMAKKDPEGLFLQDNIV
AEFSVDETGQMSATAKGRVRLLNNWDVCADMVGTFTDTEDPAKFKMKYWGVASFLQKGND
DHWIVDTDYDTYAVQYSCRLLNLDGTCADSYSFVFSRDPNGLPPEAQKIVRQRQEELCLA
RQYRLIVHNGYCDGRSERNLL
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  Blast E-value cutoff:
BDBM249482
n/a
NameBDBM249482
Synonyms:US10072016, Compound 81 | US10407433, Compound 81 | US10913746, Compound 81 | US11649240, Compound 81 | US9434727, 80 | US9434727, 81 | US9777010, Compound 81
TypeSmall organic molecule
Emp. Form.C21H21F5N4O2
Mol. Mass.456.4091
SMILESCC(=O)N1CCc2c(C1)[nH]nc2C(=O)N1CCC(CC1)c1ccc(F)c(F)c1C(F)(F)F
Structure
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