| Reaction Details |
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 | Report a problem with these data |
| Target | D(1B) dopamine receptor |
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| Ligand | BDBM50117181 |
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| Substrate/Competitor | n/a |
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| Ki | 5±n/a nM |
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| Comments | PDSP_4939 |
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| Citation |  Qandil, AM; Lewis, MM; Jassen, A; Leonard, SK; Mailman, RB; Nichols, DE Synthesis and pharmacological evaluation of substituted naphth[1,2,3-de]isoquinolines (dinapsoline analogues) as D1 and D2 dopamine receptor ligands. Bioorg Med Chem11:1451-64 (2003) [PubMed] Article |
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| More Info.: | Get all data from this article |
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| D(1B) dopamine receptor |
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| Name: | D(1B) dopamine receptor |
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| Synonyms: | D(1B) dopamine receptor | DOPAMINE D5 | DRD5_RAT | Dopamine D1B | Dopamine D5 receptor | Dopamine receptor | Drd5 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 52827.88 |
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| Organism: | RAT |
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| Description: | Dopamine D1B 0 RAT::P25115 |
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| Residue: | 475 |
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| Sequence: | MLPPGRNRTAQPARLGLQRQLAQVDAPAGSATPLGPAQVVTAGLLTLLIVWTLLGNVLVC
AAIVRSRHLRAKMTNIFIVSLAVSDLFVALLVMPWKAVAEVAGYWPFGTFCDIWVAFDIM
CSTASILNLCIISVDRYWAISRPFRYERKMTQRVALVMVGLAWTLSILISFIPVQLNWHR
DKAGSQGQEGLLSNGTPWEEGWELEGRTENCDSSLNRTYAISSSLISFYIPVAIMIVTYT
RIYRIAQVQIRRISSLERAAEHAQSCRSRGAYEPDPSLRASIKKETKVFKTLSMIMGVFV
CCWLPFFILNCMVPFCSSGDAEGPKTGFPCVSETTFDIFVWFGWANSSLNPIIYAFNADF
RKVFAQLLGCSHFCFRTPVQTVNISNELISYNQDTVFHKEIATAYVHMIPNAVSSGDREV
GEEEEEGPFDHMSQISPTTPDGDLAAESVWELDCEEEVSLGKISPLTPNCFDKTA
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| BDBM50117181 |
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| n/a |
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| Name | BDBM50117181 |
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| Synonyms: | (S)-2,3,7,11b-Tetrahydro-1H-dibenzo[de,h]isoquinoline-8,9-diol | 2,3,7,11b-Tetrahydro-1H-dibenzo[de,h]isoquinoline-8,9-diol | CHEMBL124561 | Dinapsoline, (+/-) | Dinapsoline, (R)(+) |
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| Type | Small organic molecule |
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| Emp. Form. | C16H15NO2 |
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| Mol. Mass. | 253.2958 |
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| SMILES | Oc1ccc2[C@@H]3CNCc4cccc(Cc2c1O)c34 |
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| Structure | 
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