| Reaction Details |
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 | Report a problem with these data |
| Target | D(1A) dopamine receptor |
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| Ligand | BDBM86180 |
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| Substrate/Competitor | n/a |
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| Ki | 0.69±n/a nM |
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| Comments | PDSP_1685 |
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| Citation |  Qandil, AM; Lewis, MM; Jassen, A; Leonard, SK; Mailman, RB; Nichols, DE Synthesis and pharmacological evaluation of substituted naphth[1,2,3-de]isoquinolines (dinapsoline analogues) as D1 and D2 dopamine receptor ligands. Bioorg Med Chem11:1451-64 (2003) [PubMed] Article |
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| More Info.: | Get all data from this article |
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| D(1A) dopamine receptor |
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| Name: | D(1A) dopamine receptor |
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| Synonyms: | DOPAMINE D1 | DRD1_RAT | Dopamine D1 high | Dopamine D1 low | Dopamine receptor | Dopamine receptor D1 | Dopamine1-like | Drd1 | Drd1a |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 49429.75 |
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| Organism: | RAT |
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| Description: | P18901 |
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| Residue: | 446 |
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| Sequence: | MAPNTSTMDEAGLPAERDFSFRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNF
FVISLAVSDLLVAVLVMPWKAVAEIAGFWPLGPFCNIWVAFDIMCSTASILNLCVISVDR
YWAISSPFQYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTWPLDGNFTSLED
TEDDNCDTRLSRTYAISSSLISFYIPVAIMIVTYTSIYRIAQKQIRRISALERAAVHAKN
CQTTAGNGNPVECAQSESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFISNCMVPFCGS
EETQPFCIDSITFDVFVWFGWANSSLNPIIYAFNADFQKAFSTLLGCYRLCPTTNNAIET
VSINNNGAVVFSSHHEPRGSISKDCNLVYLIPHAVGSSEDLKKEEAGGIAKPLEKLSPAL
SVILDYDTDVSLEKIQPVTHSGQHST
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| BDBM86180 |
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| n/a |
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| Name | BDBM86180 |
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| Synonyms: | CAS_87075-17-0 | NSC_5018 | SCH 23390 | SCH23390 | US9359372, SCH23390 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H18ClNO |
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| Mol. Mass. | 287.784 |
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| SMILES | CN1CCc2cc(Cl)c(O)cc2C(C1)c1ccccc1 |
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| Structure | 
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