Ki Summary new BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetCholinergic, Nicotinic Alpha6
LigandBDBM50004108
Substrate/Competitorn/a
Ki 20±n/a nM
CommentsPDSP_1311
Citation Vailati SMoretti MLonghi RRovati GEClementi FGotti C Developmental expression of heteromeric nicotinic receptor subtypes in chick retina. Mol Pharmacol 63:1329-37 (2003) [PubMed]  Article
More Info.:Get all data from this article
 
Cholinergic, Nicotinic Alpha6
Name:Cholinergic, Nicotinic Alpha6
Synonyms:n/a
Type:Enzyme Catalytic Domain
Mol. Mass.:57501.33
Organism:Chick
Description:Cholinergic, Nicotinic Alpha6 0 Chick::P49581
Residue:494
Sequence:
MHPKRRLCWCLPASGAWAFMLTSLIADTTACESEERLFHKLFSRYNQFIRPVENVSDPVT
VHFELAITQLTNVDEVNQIMETNLWLRHIWNDYKLRRDPREYDGIEFVRVPADKIWKPDI
VLYNNAVGDFQVEGKTKALLRYDGMITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWT
YDKAKIDLLIIGSKVDMNEFWENSEWEIVDASGYKHDIKYNCCEEIYTDITYSFYIRRLP
MFYTINLIIPCLFISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVI
PLVGEYLLFTMIFVTLSIVITVFVLNIHYRTPTTHTMPKWVKTVFLSLLPKVLLMQRPLE
QEKKNISKKTKKGSAKTSGKSKHSKHKDNKLHKEQRCCHCDKADDLTSTRRSRLSHQSLK
WMAEHTEYSPEVKDVINNVQFIAENMKSQNETKEVEDDWKYVAMVIDRVFLWVFIILCVF
GTAGLFIQPLIADT
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50004108
n/a
NameBDBM50004108
Synonyms:(+-)-nicotine | (R,S)-nicotine | (RS)-nicotine | 3-(1-methylpyrrolidin-2-yl)pyridine | CHEMBL440464 | Nicotin | Nicotine-(+) | Nikotin | US8609708, 54 Nicotine | US9284322, Nicotine | nicotine
TypeSmall organic molecule
Emp. Form.C10H14N2
Mol. Mass.162.2316
SMILESCN1CCCC1c1cccnc1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: