| Reaction Details |
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 | Report a problem with these data |
| Target | Neuronal acetylcholine receptor subunit alpha-6 |
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| Ligand | BDBM50004108 |
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| Substrate/Competitor | n/a |
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| Ki | 20±n/a nM |
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| Comments | PDSP_1311 |
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| Citation |  Vailati, S; Moretti, M; Longhi, R; Rovati, GE; Clementi, F; Gotti, C Developmental expression of heteromeric nicotinic receptor subtypes in chick retina. Mol Pharmacol63:1329-37 (2003) [PubMed] Article |
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| More Info.: | Get all data from this article |
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| Neuronal acetylcholine receptor subunit alpha-6 |
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| Name: | Neuronal acetylcholine receptor subunit alpha-6 |
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| Synonyms: | ACHA6_CHICK | CHRNA6 | Cholinergic, Nicotinic Alpha6 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 57501.33 |
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| Organism: | Chick |
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| Description: | Cholinergic, Nicotinic Alpha6 0 Chick::P49581 |
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| Residue: | 494 |
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| Sequence: | MHPKRRLCWCLPASGAWAFMLTSLIADTTACESEERLFHKLFSRYNQFIRPVENVSDPVT
VHFELAITQLTNVDEVNQIMETNLWLRHIWNDYKLRRDPREYDGIEFVRVPADKIWKPDI
VLYNNAVGDFQVEGKTKALLRYDGMITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWT
YDKAKIDLLIIGSKVDMNEFWENSEWEIVDASGYKHDIKYNCCEEIYTDITYSFYIRRLP
MFYTINLIIPCLFISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVI
PLVGEYLLFTMIFVTLSIVITVFVLNIHYRTPTTHTMPKWVKTVFLSLLPKVLLMQRPLE
QEKKNISKKTKKGSAKTSGKSKHSKHKDNKLHKEQRCCHCDKADDLTSTRRSRLSHQSLK
WMAEHTEYSPEVKDVINNVQFIAENMKSQNETKEVEDDWKYVAMVIDRVFLWVFIILCVF
GTAGLFIQPLIADT
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| BDBM50004108 |
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| n/a |
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| Name | BDBM50004108 |
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| Synonyms: | (+-)-nicotine | (R,S)-nicotine | (RS)-nicotine | 3-(1-methylpyrrolidin-2-yl)pyridine | CHEMBL440464 | Nicotin | Nicotine-(+) | Nikotin | US11667638, Example Nicotine | US8609708, 54 Nicotine | US9284322, Nicotine | US9993465, Nicotine | nicotine |
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| Type | Small organic molecule |
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| Emp. Form. | C10H14N2 |
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| Mol. Mass. | 162.2316 |
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| SMILES | CN1CCCC1c1cccnc1 |
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| Structure | 
|
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