| Reaction Details |
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 | Report a problem with these data |
| Target | Muscarinic acetylcholine receptor M2 |
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| Ligand | BDBM82479 |
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| Substrate/Competitor | n/a |
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| Ki | 18±n/a nM |
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| Comments | PDSP_1408 |
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| Citation |  Bymaster, FP; Felder, CC; Tzavara, E; Nomikos, GG; Calligaro, DO; Mckinzie, DL Muscarinic mechanisms of antipsychotic atypicality. Prog Neuropsychopharmacol Biol Psychiatry27:1125-43 (2003) [PubMed] Article |
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| More Info.: | Get all data from this article |
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| Muscarinic acetylcholine receptor M2 |
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| Name: | Muscarinic acetylcholine receptor M2 |
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| Synonyms: | ACM2_RAT | Cholinergic, muscarinic M2 | Chrm-2 | Chrm2 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 51555.53 |
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| Organism: | RAT |
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| Description: | P10980 |
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| Residue: | 466 |
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| Sequence: | MNNSTNSSNNGLAITSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNY
FLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFD
RYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQF
FSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKEKKEPVANQDPVSPSLVQGRI
VKPNNNNMPGGDGGLEHNKIQNGKAPRDGVTENCVQGEEKESSNDSTSVSAVASNMRDDE
ITQDENTVSTSLGHSRDDNSKQTCIKIVTKAQKGDVCTPTSTTVELVGSSGQNGDEKQNI
VARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNT
VWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR
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| BDBM82479 |
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| n/a |
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| Name | BDBM82479 |
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| Synonyms: | CAS_132539-06-1 | NSC_4585 | OLANZAPINE | USRE49340, Rank 2 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H20N4S |
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| Mol. Mass. | 312.432 |
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| SMILES | CN1CCN(CC1)C1=c2cc(C)sc2=Nc2ccccc2N1 |c:8,15| |
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| Structure | 
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