| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 6 |
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| Ligand | BDBM50073056 |
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| Substrate/Competitor | n/a |
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| Ki | 22.91±n/a nM |
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| Comments | PDSP_3219 |
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| Citation |  Hirst, WD; Abrahamsen, B; Blaney, FE; Calver, AR; Aloj, L; Price, GW; Medhurst, AD Differences in the central nervous system distribution and pharmacology of the mouse 5-hydroxytryptamine-6 receptor compared with rat and human receptors investigated by radioligand binding, site-directed mutagenesis, and molecular modeling. Mol Pharmacol64:1295-308 (2003) [PubMed] Article |
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| More Info.: | Get all data from this article |
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| 5-hydroxytryptamine receptor 6 |
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| Name: | 5-hydroxytryptamine receptor 6 |
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| Synonyms: | 5-HT6 | 5-hydroxytryptamine receptor 6 | 5HT6R_MOUSE | Htr6 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 47012.98 |
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| Organism: | MOUSE |
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| Description: | 5-HT6 HTR6 MOUSE::Q9R1C8 |
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| Residue: | 440 |
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| Sequence: | MVPEPGPVNSSTPAWGPGPPPAPGGSGWVAAALCVVIVLTAAANSLLIALICTQPALRNT
SNFFLVSLFTSDLMVGLVVMPPAMLNALYGRWVLARGLCLLWTAFDVMCCSASILNLCLI
SLDRYLLILSPLRYKLRMTAPRALALILGAWSLAALASFLPLLLGWHELGKARTSAPGQC
RLLASLPYVLVASGVTFFLPSGAICFTYCRILLAARKQAVQVASLTTGTATAGQALETLQ
VPRTPRPGMESADSRRLTTKHSRKALKASLTLGILLSMFFVTWLPFFVASIAQAVCDCIS
PGLFDVLTWLGYCNSTMNPIIYPLFMRDFKRALGRFVPCVHCPPEHRASPASPSMWTSHS
GARPGLSLQQVLPLPLPPNSDSDSASGGTSGLQLTAQLLLPGEATRDPPPPTRAPTVVNF
FVTDSVEPEIRQHPLGSPMN
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| BDBM50073056 |
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| n/a |
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| Name | BDBM50073056 |
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| Synonyms: | 4-Bromo-N-[4-methoxy-3-(4-methyl-piperazin-1-yl)-phenyl]-benzenesulfonamide | CHEMBL292759 | SB-214111 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H22BrN3O3S |
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| Mol. Mass. | 440.355 |
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| SMILES | COc1ccc(NS(=O)(=O)c2ccc(Br)cc2)cc1N1CCN(C)CC1 |
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| Structure | 
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