| Reaction Details |
|---|
 | Report a problem with these data |
| Target | D(1A) dopamine receptor |
|---|
| Ligand | BDBM86465 |
|---|
| Substrate/Competitor | n/a |
|---|
| Ki | 139±n/a nM |
|---|
| Comments | PDSP_4945 |
|---|
| Citation |  Sit, SY; Xie, K; Jacutin-Porte, S; Boy, KM; Seanz, J; Taber, MT; Gulwadi, AG; Korpinen, CD; Burris, KD; Molski, TF; Ryan, E; Xu, C; Verdoorn, T; Johnson, G; Nichols, DE; Mailman, RB Synthesis and SAR exploration of dinapsoline analogues. Bioorg Med Chem12:715-34 (2004) [PubMed] Article |
|---|
| More Info.: | Get all data from this article |
|---|
| |
| D(1A) dopamine receptor |
|---|
| Name: | D(1A) dopamine receptor |
|---|
| Synonyms: | DOPAMINE D1 | DRD1_RAT | Dopamine D1 high | Dopamine D1 low | Dopamine receptor | Dopamine receptor D1 | Dopamine1-like | Drd1 | Drd1a |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 49429.75 |
|---|
| Organism: | RAT |
|---|
| Description: | P18901 |
|---|
| Residue: | 446 |
|---|
| Sequence: | MAPNTSTMDEAGLPAERDFSFRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNF
FVISLAVSDLLVAVLVMPWKAVAEIAGFWPLGPFCNIWVAFDIMCSTASILNLCVISVDR
YWAISSPFQYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTWPLDGNFTSLED
TEDDNCDTRLSRTYAISSSLISFYIPVAIMIVTYTSIYRIAQKQIRRISALERAAVHAKN
CQTTAGNGNPVECAQSESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFISNCMVPFCGS
EETQPFCIDSITFDVFVWFGWANSSLNPIIYAFNADFQKAFSTLLGCYRLCPTTNNAIET
VSINNNGAVVFSSHHEPRGSISKDCNLVYLIPHAVGSSEDLKKEEAGGIAKPLEKLSPAL
SVILDYDTDVSLEKIQPVTHSGQHST
|
|
|
|---|
| BDBM86465 |
|---|
| n/a |
|---|
| Name | BDBM86465 |
|---|
| Synonyms: | (+/-)-7-methyldinapsoline hydrobromide |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C17H17NO2 |
|---|
| Mol. Mass. | 267.3224 |
|---|
| SMILES | CC1c2cccc3CNC[C@@H](c4ccc(O)c(O)c14)c23 |
|---|
| Structure | 
|
|---|
Search and Browse
