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TargetD(2) dopamine receptor
LigandBDBM86459
Substrate/Competitorn/a
Ki 28±n/a nM
CommentsPDSP_4961
Citation Sit, SYXie, KJacutin-Porte, SBoy, KMSeanz, JTaber, MTGulwadi, AGKorpinen, CDBurris, KDMolski, TFRyan, EXu, CVerdoorn, TJohnson, GNichols, DEMailman, RB Synthesis and SAR exploration of dinapsoline analogues. Bioorg Med Chem12:715-34 (2004) [PubMed]  Article
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D(2) dopamine receptor
Name:D(2) dopamine receptor
Synonyms:DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:50931.60
Organism:Rattus norvegicus (rat)
Description:P61169
Residue:444
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVS
REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTA
SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQN
ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPL
KGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPP
SHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMS
RRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNS
AVNPIIYTTFNIEFRKAFMKILHC
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  Blast E-value cutoff:
BDBM86459
n/a
NameBDBM86459
Synonyms:4-fluorodinapsoline hydrobromide | CAS_0 | NSC_0
TypeSmall organic molecule
Emp. Form.C16H14FNO2
Mol. Mass.271.2863
SMILESOc1ccc2[C@@H]3CNCc4c(F)ccc(Cc2c1O)c34
Structure
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