| Reaction Details |
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 | Report a problem with these data |
| Target | Neuronal acetylcholine receptor subunit alpha-2 |
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| Ligand | BDBM50066789 |
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| Substrate/Competitor | n/a |
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| Ki | 41±n/a nM |
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| Comments | PDSP_4117 |
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| Citation |  Xiao, Y; Kellar, KJ The comparative pharmacology and up-regulation of rat neuronal nicotinic receptor subtype binding sites stably expressed in transfected mammalian cells. J Pharmacol Exp Ther310:98-107 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article |
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| Neuronal acetylcholine receptor subunit alpha-2 |
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| Name: | Neuronal acetylcholine receptor subunit alpha-2 |
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| Synonyms: | ACHA2_RAT | Acra2 | Cholinergic, Nicotinic Alpha2Beta2 | Cholinergic, Nicotinic Alpha2Beta4 | Chrna2 |
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| Type: | Enzyme |
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| Mol. Mass.: | 58597.25 |
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| Organism: | Rattus norvegicus (Rat) |
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| Description: | P12389 |
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| Residue: | 511 |
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| Sequence: | MTLSHSALQFWTHLYLWCLLLVPAVLTQQGSHTHAEDRLFKHLFGGYNRWARPVPNTSDV
VIVRFGLSIAQLIDVDEKNQMMTTNVWLKQEWNDYKLRWDPAEFGNVTSLRVPSEMIWIP
DIVLYNNADGEFAVTHMTKAHLFFTGTVHWVPPAIYKSSCSIDVTFFPFDQQNCKMKFGS
WTYDKAKIDLEQMERTVDLKDYWESGEWAIINATGTYNSKKYDCCAEIYPDVTYYFVIRR
LPLFYTINLIIPCLLISCLTVLVFYLPSECGEKITLCISVLLSLTVFLLLITEIIPSTSL
VIPLIGEYLLFTMIFVTLSIVITVFVLNVHHRSPSTHNMPNWVRVALLGRVPRWLMMNRP
LPPMELHGSPDLKLSPSYHWLETNMDAGEREETEEEEEEEDENICVCAGLPDSSMGVLYG
HGGLHLRAMEPETKTPSQASEILLSPQIQKALEGVHYIADRLRSEDADSSVKEDWKYVAM
VVDRIFLWLFIIVCFLGTIGLFLPPFLAGMI
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| BDBM50066789 |
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| n/a |
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| Name | BDBM50066789 |
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| Synonyms: | 3-((S)-1-Azetidin-2-ylmethoxy)-5-iodo-pyridine | A-85380,5-Iodo | A-85380-I | CHEMBL123433 |
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| Type | Small organic molecule |
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| Emp. Form. | C9H11IN2O |
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| Mol. Mass. | 290.1009 |
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| SMILES | Ic1cncc(OC[C@@H]2CCN2)c1 |
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| Structure | 
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